Cdx1 and c-Myc Foster the Initiation of Transdifferentiation of the Normal Esophageal Squamous Epithelium toward Barrett's Esophagus

BACKGROUND: Barrett's esophagus is a premalignant condition whereby the normal stratified squamous esophageal epithelium undergoes a transdifferentiation program resulting in a simple columnar epithelium reminiscent of the small intestine. These changes are typically associated with the stratif...

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Hlavní autoři: Stairs, Douglas B., Nakagawa, Hiroshi, Klein-Szanto, Andres, Mitchell, Shukriyyah D., Silberg, Debra G., Tobias, John W., Lynch, John P., Rustgi, Anil K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2008
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2568822/
https://ncbi.nlm.nih.gov/pubmed/18953412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003534
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