IGFBP-3 Regulates Esophageal Tumor Growth Through IGF-Dependent and Independent Mechanisms

Insulin-like growth factor binding protein (IGFBP)-3 exerts either proapoptotic or growth stimulatory effects depending upon the cellular context. IGFBP-3 is overexpressed frequently in esophageal cancer. Yet, the role of IGFBP-3 in esophageal tumor biology remains elusive. To delineate the function...

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Detalhes bibliográficos
Main Authors: Takaoka, Munenori, Kim, Seok-Hyun, Okawa, Takaomi, Michaylira, Carmen Z., Stairs, Douglas B., Johnstone, Cameron N., Andl, Claudia D., Rhoades, Ben, Lee, James J., Klein-Szanto, Andres J.P., El-Deiry, Wafik S., Nakagawa, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993006/
https://ncbi.nlm.nih.gov/pubmed/17457048
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