EGF-mediated regulation of IGFBP-3 determines esophageal epithelial cellular response to IGF-I

IGF and EGF regulate various physiological and pathological processes. IGF binding protein (IGFBP)-3 regulates cell proliferation in IGF-dependent and -independent fashions. Recently, we identified IGFBP-3 as a novel EGF receptor (EGFR) downstream target molecule in primary and immortalized human es...

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Autores principales: Takaoka, Munenori, Smith, Caitlin E., Mashiba, Michael K., Okawa, Takaomi, Andl, Claudia D., El-Deiry, Wafik S., Nakagawa, Hiroshi
Formato: Artigo
Lenguaje:Inglês
Publicado: 2005
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996094/
https://ncbi.nlm.nih.gov/pubmed/16210470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00344.2005
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