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AKT induces senescence in primary esophageal epithelial cells but is permissive for differentiation as revealed in organotypic culture

Epidermal growth factor receptor (EGFR) overexpression and activation is critical in the initiation and progression of cancers, especially those of epithelial origin. EGFR activation is associated with the induction of divergent signal transduction pathways and a gamut of cellular processes; however...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Oyama, K, Okawa, T, Nakagawa, H, Takaoka, M, Andl, CD, Kim, S-H, Klein-Szanto, A, Diehl, JA, Herlyn, M, El-Deiry, W, Rustgi, AK
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2006
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996093/
https://ncbi.nlm.nih.gov/pubmed/17043653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210025
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