Being Flexible: The Voltage-Controllable Activation Gate of Kv Channels

Por Labro, Alain J., Snyders, Dirk J.
Publicado em 2012

Independent movement of the voltage sensors in K(V)2.1/K(V)6.4 heterotetramers

Por Bocksteins, Elke, Snyders, Dirk J., Holmgren, Miguel
Publicado no Sci Rep (2017)

Coupling of Voltage Sensing to Channel Opening Reflects Intrasubunit Interactions in Kv Channels

Por Labro, Alain J., Raes, Adam L., Snyders, Dirk J.
Publicado em 2005

Mutations in the S6 Gate Isolate a Late Step in the Activation Pathway and Reduce 4-AP Sensitivity in Shaker K(v) Channel

Por Martinez-Morales, Evelyn, Snyders, Dirk J., Labro, Alain J.
Publicado em 2014

Domain analysis of Kv6.3, an electrically silent channel

Por Ottschytsch, Natacha, Raes, Adam L, Timmermans, Jean-Pierre, Snyders, Dirk J
Publicado em 2005

The Electrically Silent Kv6.4 Subunit Confers Hyperpolarized Gating Charge Movement in Kv2.1/Kv6.4 Heterotetrameric Channels

Por Bocksteins, Elke, Labro, Alain J., Snyders, Dirk J., Mohapatra, Durga P.
Publicado em 2012

Modulation of Closed−State Inactivation in Kv2.1/Kv6.4 Heterotetramers as Mechanism for 4−AP Induced Potentiation

Por Stas, Jeroen I., Bocksteins, Elke, Labro, Alain J., Snyders, Dirk J.
Publicado no PLoS One (2015)

Alkanols inhibit voltage-gated K(+) channels via a distinct gating modifying mechanism that prevents gate opening

Por Martínez-Morales, Evelyn, Kopljar, Ivan, Snyders, Dirk J., Labro, Alain J.
Publicado no Sci Rep (2015)

Role of the S6 C-terminus in KCNQ1 channel gating

Por Boulet, Inge R, Labro, Alain J, Raes, Adam L, Snyders, Dirk J
Publicado em 2007

The anticonvulsant retigabine suppresses neuronal K(V)2-mediated currents

Por Stas, Jeroen I., Bocksteins, Elke, Jensen, Camilla S., Schmitt, Nicole, Snyders, Dirk J.
Publicado no Sci Rep (2016)

Determining the correct stoichiometry of Kv2.1/Kv6.4 heterotetramers, functional in multiple stoichiometrical configurations

Por Möller, Lena, Regnier, Glenn, Labro, Alain J., Blunck, Rikard, Snyders, Dirk J.
Publicado no Proc Natl Acad Sci U S A (2020)

Reply to Pisupati et al.: Evaluating single subunit counting data to find the correct stoichiometry

Por Möller, Lena, Regnier, Glenn, Labro, Alain J., Snyders, Dirk J., Blunck, Rikard
Publicado no Proc Natl Acad Sci U S A (2020)

K(v)3.1 uses a timely resurgent K(+) current to secure action potential repolarization

Por Labro, Alain J., Priest, Michael F., Lacroix, Jérôme J., Snyders, Dirk J., Bezanilla, Francisco
Publicado no Nat Commun (2015)

Molecular mechanism for depolarization-induced modulation of Kv channel closure

Por Labro, Alain J., Lacroix, Jerome J., Villalba-Galea, Carlos A., Snyders, Dirk J., Bezanilla, Francisco
Publicado em 2012

The Subfamily-Specific Interaction between Kv2.1 and Kv6.4 Subunits Is Determined by Interactions between the N- and C-termini

Por Bocksteins, Elke, Mayeur, Evy, Van Tilborg, Abbi, Regnier, Glenn, Timmermans, Jean-Pierre, Snyders, Dirk J.
Publicado em 2014

The contribution of Kv2.2‐mediated currents decreases during the postnatal development of mouse dorsal root ganglion neurons

Por Regnier, Glenn, Bocksteins, Elke, Van de Vijver, Gerda, Snyders, Dirk J., van Bogaert, Pierre‐Paul
Publicado no Physiol Rep (2016)

Hydrophobic Drug/Toxin Binding Sites in Voltage-Dependent K(+) and Na(+) Channels

Por Van Theemsche, Kenny M., Van de Sande, Dieter V., Snyders, Dirk J., Labro, Alain J.
Publicado no Front Pharmacol (2020)

The ladder-shaped polyether toxin gambierol anchors the gating machinery of Kv3.1 channels in the resting state

Por Kopljar, Ivan, Labro, Alain J., de Block, Tessa, Rainier, Jon D., Tytgat, Jan, Snyders, Dirk J.
Publicado em 2013

Gambierol and n-alkanols inhibit Shaker Kv channel via distinct binding sites outside the K(+) pore

Por Martínez-Morales, Evelyn, Kopljar, Ivan, Rainier, Jon D., Tytgat, Jan, Snyders, Dirk J., Labro, Alain J.
Publicado no Toxicon (2016)

The Selectivity Filter Is Involved in the U-Type Inactivation Process of Kv2.1 and Kv3.1 Channels

Por Coonen, Laura, Mayeur, Evy, De Neuter, Nicolas, Snyders, Dirk J., Cuello, Luis G., Labro, Alain J.
Publicado no Biophys J (2020)