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Role of the S6 C-terminus in KCNQ1 channel gating
Co-assembly of KCNQ1 α-subunits with KCNE1 β-subunits results in the channel complex underlying the cardiac I(Ks) current in vivo. Like other voltage-gated K(+) channels, KCNQ1 has a tetrameric configuration. The S6 segment of each subunit lines the ion channel pore with the lower part forming the a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2375480/ https://ncbi.nlm.nih.gov/pubmed/17932138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.145813 |
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