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Coupling of Voltage Sensing to Channel Opening Reflects Intrasubunit Interactions in Kv Channels

Voltage-gated K(+) channels play a central role in the modulation of excitability. In these channels, the voltage-dependent movement of the voltage sensor (primarily S4) is coupled to the (S6) gate that opens the permeation pathway. Because of the tetrameric structure, such coupling could occur with...

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Bibliografski detalji
Glavni autori: Labro, Alain J., Raes, Adam L., Snyders, Dirk J.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217479/
https://ncbi.nlm.nih.gov/pubmed/15623896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200409194
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