The Subfamily-Specific Interaction between Kv2.1 and Kv6.4 Subunits Is Determined by Interactions between the N- and C-termini

The “silent” voltage-gated potassium (KvS) channel subunit Kv6.4 does not form electrically functional homotetramers at the plasma membrane but assembles with Kv2.1 subunits, generating functional Kv2.1/Kv6.4 heterotetramers. The N-terminal T1 domain determines the subfamily-specific assembly of Kv1...

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Autores principales: Bocksteins, Elke, Mayeur, Evy, Van Tilborg, Abbi, Regnier, Glenn, Timmermans, Jean-Pierre, Snyders, Dirk J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047056/
https://ncbi.nlm.nih.gov/pubmed/24901643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098960
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