Targeting acute myeloid leukemia stem cell signaling by natural products

Por Siveen, Kodappully Sivaraman, Uddin, Shahab, Mohammad, Ramzi M.
Publicado no Mol Cancer (2017)

Phytochemicals in Cancer Prevention and Therapy

Por Pratheeshkumar, Poyil, Son, Young-Ok, Korangath, Preethi, Manu, Kanjoormana Aryan, Siveen, Kodappully Sivaraman
Publicado no Biomed Res Int (2015)

Oleanane triterpenoids in the prevention and therapy of breast cancer: current evidence and future perspectives

Por Parikh, Nisha R., Mandal, Animesh, Bhatia, Deepak, Siveen, Kodappully Sivaraman, Sethi, Gautam, Bishayee, Anupam
Publicado no Phytochem Rev (2014)

Role of Non Receptor Tyrosine Kinases in Hematological Malignances and its Targeting by Natural Products

Por Siveen, Kodappully S., Prabhu, Kirti S., Achkar, Iman W., Kuttikrishnan, Shilpa, Shyam, Sunitha, Khan, Abdul Q., Merhi, Maysaloun, Dermime, Said, Uddin, Shahab
Publicado no Mol Cancer (2018)

Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in multiple myeloma xenograft mouse mod...

Por Siveen, Kodappully Sivaraman, Mustafa, Nurulhuda, Li, Feng, Kannaiyan, Radhamani, Ahn, Kwang Seok, Kumar, Alan Prem, Chng, Wee-Joo, Sethi1, Gautam
Publicado em 2013

Celastrol Attenuates the Invasion and Migration and Augments the Anticancer Effects of Bortezomib in a Xenograft Mouse Model of Multiple Myeloma

Por Shanmugam, Muthu K., Ahn, Kwang S., Lee, Jong H., Kannaiyan, Radhamani, Mustafa, Nurulhuda, Manu, Kanjoormana A., Siveen, Kodappully S., Sethi, Gautam, Chng, Wee J., Kumar, Alan P.
Publicado no Front Pharmacol (2018)

Bortezomib-mediated downregulation of S-phase kinase protein-2 (SKP2) causes apoptotic cell death in chronic myelogenous leukemia cells

Por Iskandarani, Ahmad, Bhat, Ajaz A., Siveen, Kodappully S., Prabhu, Kirti S., Kuttikrishnan, Shilpa, Khan, Muzammil A., Krishnankutty, Roopesh, Kulinski, Michal, Nasr, Rihab R., Mohammad, Ramzi M., Uddin, Shahab
Publicado no J Transl Med (2016)

Novel Synthetic Biscoumarins Target Tumor Necrosis Factor-α in Hepatocellular Carcinoma in Vitro and in Vivo

Por Keerthy, Hosadurga Kumar, Mohan, Chakrabhavi Dhananjaya, Siveen, Kodappully Sivaraman, Fuchs, Julian E., Rangappa, Shobith, Sundaram, Mahalingam S., Li, Feng, Girish, Kesturu S., Sethi, Gautam, Basappa, Bender, Andreas, Rangappa, Kanchugarakoppal Subbegowda
Publicado no J Biol Chem (2014)

γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model

Por Siveen, Kodappully Sivaraman, Ahn, Kwang Seok, Ong, Tina H., Shanmugam, Muthu K., Li, Feng, Yap, Wei Ney, Kumar, Alan Prem, Fong, Chee Wai, Tergaonkar, Vinay, Hui, Kam M., Sethi, Gautam
Publicado em 2014

Targeting of X-linked inhibitor of apoptosis protein and PI3-kinase/AKT signaling by embelin suppresses growth of leukemic cells

Por Prabhu, Kirti S., Siveen, Kodappully S., Kuttikrishnan, Shilpa, Iskandarani, Ahmad, Tsakou, Magdalini, Achkar, Iman W., Therachiyil, Lubna, Krishnankutty, Roopesh, Parray, Aijaz, Kulinski, Michal, Merhi, Maysaloun, Dermime, Said, Mohammad, Ramzi M., Uddin, Shahab
Publicado no PLoS One (2017)

Greensporone C, a Freshwater Fungal Secondary Metabolite Induces Mitochondrial-Mediated Apoptotic Cell Death in Leukemic Cell Lines

Por Prabhu, Kirti S., Siveen, Kodappully Sivaraman, Kuttikrishnan, Shilpa, Iskandarani, Ahmad N., Khan, Abdul Q., Merhi, Maysaloun, Omri, Halima E., Dermime, Said, El-Elimat, Tamam, Oberlies, Nicholas H., Alali, Feras Q., Uddin, Shahab
Publicado no Front Pharmacol (2018)

Emodin Suppresses Migration and Invasion through the Modulation of CXCR4 Expression in an Orthotopic Model of Human Hepatocellular Carcinoma

Por Manu, Kanjoormana Aryan, Shanmugam, Muthu K., Ong, Tina H., Subramaniam, Aruljothi, Siveen, Kodappully Sivaraman, Perumal, Ekambaram, Samy, Ramar Perumal, Bist, Pradeep, Lim, Lina H. K., Kumar, Alan Prem, Hui, Kam M., Sethi, Gautam
Publicado em 2013

Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3

Por Dai, Xiaoyun, Ahn, Kwang Seok, Kim, Chulwon, Siveen, Kodappully Sivaraman, Ong, Tina H., Shanmugam, Muthu K., Li, Feng, Shi, Jizhong, Kumar, Alan Prem, Wang, Ling Zhi, Goh, Boon Cher, Magae, Junji, Hui, Kam M., Sethi, Gautam
Publicado no Mol Oncol (2015)

Isorhamnetin Inhibits Proliferation and Invasion and Induces Apoptosis through the Modulation of Peroxisome Proliferator-activated Receptor γ Activation Pathway in Gastric Cancer

Por Ramachandran, Lalitha, Manu, Kanjoormana Aryan, Shanmugam, Muthu K., Li, Feng, Siveen, Kodappully Sivaraman, Vali, Shireen, Kapoor, Shweta, Abbasi, Taher, Surana, Rohit, Smoot, Duane T., Ashktorab, Hassan, Tan, Patrick, Ahn, Kwang Seok, Yap, Chun Wei, Kumar, Alan Prem, Sethi, Gautam
Publicado em 2012

Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancer.

Por Ramachandran, Lalitha, Manu, Kanjoormana Aryan, Shanmugam, Muthu K., Li, Feng, Siveen, Kodappully Sivaraman, Vali, Shireen, Kapoor, Shweta, Abbasi, Taher, Surana, Rohit, Smoot, Duane T., Ashktorab, Hassan, Tan, Patrick, Ahn, Kwang Seok, Yap, Chun Wei, Kumar, Alan Prem, Sethi, Gautam
Publicado em 2013

Development of Novel Triazolo-Thiadiazoles from Heterogeneous “Green” Catalysis as Protein Tyrosine Phosphatase 1B Inhibitors

Por Baburajeev, C. P., Dhananjaya Mohan, Chakrabhavi, Ananda, Hanumappa, Rangappa, Shobith, Fuchs, Julian E., Jagadish, Swamy, Sivaraman Siveen, Kodappully, Chinnathambi, Arunachalam, Ali Alharbi, Sulaiman, Zayed, M. E., Zhang, Jingwen, Li, Feng, Sethi, Gautam, Girish, Kesturu S., Bender, Andreas, Basappa, Rangappa, Kanchugarakoppal S.
Publicado no Sci Rep (2015)

Inhibition of p300 lysine acetyltransferase activity by luteolin reduces tumor growth in head and neck squamous cell carcinoma (HNSCC) xenograft mouse model

Por Selvi, Ruthrotha B., Swaminathan, Amrutha, Chatterjee, Snehajyoti, Shanmugam, Muthu K., Li, Feng, Ramakrishnan, Gowsica B., Siveen, Kodappully Sivaraman, Chinnathambi, Arunachalam, Zayed, M. Emam, Alharbi, Sulaiman Ali, Basha, Jeelan, Bhat, Akshay, Vasudevan, Madavan, Dharmarajan, Arunasalam, Sethi, Gautam, Kundu, Tapas K.
Publicado no Oncotarget (2015)

Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers

Por Li, Feng, Shanmugam, Muthu K., Siveen, Kodappully Sivaraman, Wang, Fan, Ong, Tina H., Loo, Ser Yue, Swamy, Mahadeva M.M., Mandal, Somnath, Kumar, Alan Prem, Goh, Boon Cher, Kundu, Tapas, Ahn, Kwang Seok, Wang, Ling Zhi, Hui, Kam Man, Sethi, Gautam
Publicado no Oncotarget (2015)