Celastrol Attenuates the Invasion and Migration and Augments the Anticancer Effects of Bortezomib in a Xenograft Mouse Model of Multiple Myeloma

Several lines of evidence have demonstrated that deregulated activation of NF-κB plays a pivotal role in the initiation and progression of a variety of cancers including multiple myeloma (MM). Therefore, novel molecules that can effectively suppress deregulated NF-κB upregulation can potentially red...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Shanmugam, Muthu K., Ahn, Kwang S., Lee, Jong H., Kannaiyan, Radhamani, Mustafa, Nurulhuda, Manu, Kanjoormana A., Siveen, Kodappully S., Sethi, Gautam, Chng, Wee J., Kumar, Alan P.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943600/
https://ncbi.nlm.nih.gov/pubmed/29773987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00365
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