Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers

Platinum compounds such as cisplatin and carboplatin are frequently used as the first-line chemotherapy for the treatment of the head and neck squamous cell carcinoma (HNSCC). In the present study, we investigated whether garcinol, a polyisoprenylated benzophenone can chemosensitize HNSCC to cisplat...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Li, Feng, Shanmugam, Muthu K., Siveen, Kodappully Sivaraman, Wang, Fan, Ong, Tina H., Loo, Ser Yue, Swamy, Mahadeva M.M., Mandal, Somnath, Kumar, Alan Prem, Goh, Boon Cher, Kundu, Tapas, Ahn, Kwang Seok, Wang, Ling Zhi, Hui, Kam Man, Sethi, Gautam
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467139/
https://ncbi.nlm.nih.gov/pubmed/25762616
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