Protein–DNA binding: complexities and multi-protein codes

Por Siggers, Trevor, Gordân, Raluca
Publicado em 2014

Structure-based prediction of C(2)H(2) zinc-finger binding specificity: sensitivity to docking geometry

Por Siggers, Trevor W., Honig, Barry
Publicado em 2007

Using protein-binding microarrays to study transcription factor specificity: homologs, isoforms and complexes

Por Andrilenas, Kellen K., Penvose, Ashley, Siggers, Trevor
Publicado no Brief Funct Genomics (2015)

Diversification of Transcription Factor Paralogs via Noncanonical Modularity in C2H2 Zinc Finger DNA Binding

Por Siggers, Trevor, Reddy, Jessica, Barron, Brian, Bulyk, Martha L.
Publicado em 2014

Comprehensive study of nuclear receptor DNA binding provides a revised framework for understanding receptor specificity

Por Penvose, Ashley, Keenan, Jessica L., Bray, David, Ramlall, Vijendra, Siggers, Trevor
Publicado no Nat Commun (2019)

Non-DNA-binding cofactors enhance DNA-binding specificity of a transcriptional regulatory complex

Por Siggers, Trevor, Duyzend, Michael H, Reddy, Jessica, Khan, Sidra, Bulyk, Martha L
Publicado em 2011

DNA-binding landscape of IRF3, IRF5 and IRF7 dimers: implications for dimer-specific gene regulation

Por Andrilenas, Kellen K, Ramlall, Vijendra, Kurland, Jesse, Leung, Brandon, Harbaugh, Allen G, Siggers, Trevor
Publicado no Nucleic Acids Res (2018)

Precise temporal control of the eye regulatory gene Pax6 via enhancer-binding site affinity

Por Rowan, Sheldon, Siggers, Trevor, Lachke, Salil A., Yue, Yingzi, Bulyk, Martha L., Maas, Richard L.
Publicado em 2010

Grhl2 is required in non-neural tissues for neural progenitor survival and forebrain development

Por Menke, Chelsea, Cionni, Megan, Siggers, Trevor, Bulyk, Martha L., Beier, David R., Stottmann, Rolf W.
Publicado no Genesis (2015)

NextPBM: a platform to study cell-specific transcription factor binding and cooperativity

Por Mohaghegh, Nima, Bray, David, Keenan, Jessica, Penvose, Ashley, Andrilenas, Kellen K, Ramlall, Vijendra, Siggers, Trevor
Publicado no Nucleic Acids Res (2019)

DNA-Binding and -Bending Activities of SAP30L and SAP30 Are Mediated by a Zinc-Dependent Module and Monophosphoinositides

Por Viiri, Keijo M., Jänis, Janne, Siggers, Trevor, Heinonen, Taisto Y. K., Valjakka, Jarkko, Bulyk, Martha L., Mäki, Markku, Lohi, Olli
Publicado em 2009

Principles of dimer-specific gene regulation revealed by a comprehensive characterization of NF-κB family DNA binding

Por Siggers, Trevor, Chang, Abraham B, Teixeira, Ana, Wong, Daniel, Williams, Kevin J, Ahmed, Bilal, Ragoussis, Jiannis, Udalova, Irina A, Smale, Stephen T, Bulyk, Martha L
Publicado em 2011

Extensive characterization of NF-κB binding uncovers non-canonical motifs and advances the interpretation of genetic functional traits

Por Wong, Daniel, Teixeira, Ana, Oikonomopoulos, Spyros, Humburg, Peter, Lone, Imtiaz Nisar, Saliba, David, Siggers, Trevor, Bulyk, Martha, Angelov, Dimitar, Dimitrov, Stefan, Udalova, Irina A, Ragoussis, Jiannis
Publicado em 2011

Transcription factor NF-κB is modulated by symbiotic status in a sea anemone model of cnidarian bleaching

Por Mansfield, Katelyn M., Carter, Nicole M., Nguyen, Linda, Cleves, Phillip A., Alshanbayeva, Anar, Williams, Leah M., Crowder, Camerron, Penvose, Ashley R., Finnerty, John R., Weis, Virginia M., Siggers, Trevor W., Gilmore, Thomas D.
Publicado no Sci Rep (2017)

Expansion of GA Dinucleotide Repeats Increases the Density of CLAMP Binding Sites on the X-Chromosome to Promote Drosophila Dosage Compensation

Por Kuzu, Guray, Kaye, Emily G., Chery, Jessica, Siggers, Trevor, Yang, Lin, Dobson, Jason R., Boor, Sonia, Bliss, Jacob, Liu, Wei, Jogl, Gerwald, Rohs, Remo, Singh, Nadia D., Bulyk, Martha L., Tolstorukov, Michael Y., Larschan, Erica
Publicado no PLoS Genet (2016)

Selective deployment of transcription factor paralogs with submaximal strength facilitates gene regulation in the immune system

Por Bruno, Ludovica, Ramlall, Vijendra, Studer, Romain A., Sauer, Stephan, Bradley, David, Dharmalingam, Gopuraja, Carroll, Thomas, Ghoneim, Mohamed, Chopin, Michaël, Nutt, Stephen L., Elderkin, Sarah, Rueda, David S., Fisher, Amanda G., Siggers, Trevor, Beltrao, Pedro, Merkenschlager, Matthias
Publicado no Nat Immunol (2019)

The CLAMP protein links the MSL complex to the X chromosome during Drosophila dosage compensation

Por Soruco, Marcela M.L., Chery, Jessica, Bishop, Eric P., Siggers, Trevor, Tolstorukov, Michael Y., Leydon, Alexander R., Sugden, Arthur U., Goebel, Karen, Feng, Jessica, Xia, Peng, Vedenko, Anastasia, Bulyk, Martha L., Park, Peter J., Larschan, Erica
Publicado em 2013

Survey of variation in human transcription factors reveals prevalent DNA binding changes

Por Barrera, Luis A., Vedenko, Anastasia, Kurland, Jesse V., Rogers, Julia M., Gisselbrecht, Stephen S., Rossin, Elizabeth J., Woodard, Jaie, Mariani, Luca, Kock, Kian Hong, Inukai, Sachi, Siggers, Trevor, Shokri, Leila, Gordân, Raluca, Sahni, Nidhi, Cotsapas, Chris, Hao, Tong, Yi, Song, Kellis, Manolis, Daly, Mark J., Vidal, Marc, Hill, David E., Bulyk, Martha L.
Publicado no Science (2016)