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Diversification of Transcription Factor Paralogs via Noncanonical Modularity in C2H2 Zinc Finger DNA Binding
A major challenge in obtaining a full molecular description of evolutionary adaptation is to characterize how transcription factor (TF) DNA binding specificity can change. To identify mechanisms of TF diversification, we performed detailed comparisons of yeast C2H2 ZF proteins with identical canonic...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4142112/ https://ncbi.nlm.nih.gov/pubmed/25042805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.06.019 |
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