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Precise temporal control of the eye regulatory gene Pax6 via enhancer-binding site affinity
How transcription factors interpret the cis-regulatory logic encoded within enhancers to mediate quantitative changes in spatiotemporally restricted expression patterns during animal development is not well understood. Pax6 is a dosage-sensitive gene essential for eye development. Here, we identify...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867212/ https://ncbi.nlm.nih.gov/pubmed/20413611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1890410 |
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