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Precise temporal control of the eye regulatory gene Pax6 via enhancer-binding site affinity

How transcription factors interpret the cis-regulatory logic encoded within enhancers to mediate quantitative changes in spatiotemporally restricted expression patterns during animal development is not well understood. Pax6 is a dosage-sensitive gene essential for eye development. Here, we identify...

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Bibliografski detalji
Glavni autori: Rowan, Sheldon, Siggers, Trevor, Lachke, Salil A., Yue, Yingzi, Bulyk, Martha L., Maas, Richard L.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867212/
https://ncbi.nlm.nih.gov/pubmed/20413611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1890410
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