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Pax6- and Six3-Mediated Induction of Lens Cell Fate in Mouse and Human ES Cells

Embryonic stem (ES) cells provide a potentially useful in vitro model for the study of in vivo tissue differentiation. We used mouse and human ES cells to investigate whether the lens regulatory genes Pax6 and Six3 could induce lens cell fate in vitro. To help assess the onset of lens differentiatio...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Anchan, Raymond M., Lachke, Salil A., Gerami-Naini, Behzad, Lindsey, Jennifer, Ng, Nicholas, Naber, Catherine, Nickerson, Michael, Cavallesco, Resy, Rowan, Sheldon, Eaton, Jennifer L., Xi, Qiongchao, Maas, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269389/
https://ncbi.nlm.nih.gov/pubmed/25517354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115106
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