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NextPBM: a platform to study cell-specific transcription factor binding and cooperativity

High-throughput (HT) in vitro methods for measuring protein-DNA binding have become invaluable for characterizing transcription factor (TF) complexes and modeling gene regulation. However, current methods do not utilize endogenous proteins and, therefore, do not quantify the impact of cell-specific...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Mohaghegh, Nima, Bray, David, Keenan, Jessica, Penvose, Ashley, Andrilenas, Kellen K, Ramlall, Vijendra, Siggers, Trevor
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451091/
https://ncbi.nlm.nih.gov/pubmed/30657937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz020
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