Functional characterization of a novel somatic oncogenic mutation of PIK3CB

Por Whale, Andrew D, Colman, Lucy, Lensun, Letitia, Rogers, Helen L, Shuttleworth, Stephen J
Publicado no Signal Transduct Target Ther (2017)

Exploring the specificity of the PI3K family inhibitor LY294002

Por Gharbi, Severine I., Zvelebil, Marketa J., Shuttleworth, Stephen J., Hancox, Tim, Saghir, Nahid, Timms, John F., Waterfield, Michael D.
Publicado em 2007

Compensation between CSF1R(+) macrophages and Foxp3(+) Treg cells drives resistance to tumor immunotherapy

Por Gyori, David, Lim, Ee Lyn, Grant, Francis M., Spensberger, Dominik, Roychoudhuri, Rahul, Shuttleworth, Stephen J., Okkenhaug, Klaus, Stephens, Len R., Hawkins, Phillip T.
Publicado no JCI Insight (2018)

Biological properties of potent inhibitors of class I phosphatidylinositide 3-kinases: from PI-103 through PI-540, PI-620 to the oral agent GDC-0941

Por Raynaud, Florence I., Eccles, Suzanne A., Patel, Sonal, Alix, Sonia, Box, Gary, Chuckowree, Irina, Folkes, Adrian, Gowan, Sharon, De Haven Brandon, Alexis, Di Stefano, Francesca, Hayes, Angela, Henley, Alan T., Lensun, Letitia, Pergl-Wilson, Giles, Robson, Anthony, Saghir, Nahid, Zhyvoloup, Alexander, McDonald, Edward, Sheldrake, Peter, Shuttleworth, Stephen, Valenti, Melanie, Wan, Nan Chi, Clarke, Paul A., Workman, Paul
Publicado em 2009