Finding the needle in the haystack: why high-throughput screening is good for your health

Por Aherne, G Wynne, McDonald, Edward, Workman, Paul
Publicado em 2002

Fadraciclib (CYC065), a novel CDK inhibitor, targets key pro-survival and oncogenic pathways in cancer

Por Frame, Sheelagh, Saladino, Chiara, MacKay, Craig, Atrash, Butrus, Sheldrake, Peter, McDonald, Edward, Clarke, Paul A., Workman, Paul, Blake, David, Zheleva, Daniella
Publicado no PLoS One (2020)

Novel Clinical and Pathologic Findings in a Heartland Virus-Associated Death

Por Fill, Mary-Margaret A., Compton, Margaret L., McDonald, Edward C., Moncayo, Abelardo C., Dunn, John R., Schaffner, William, Bhatnagar, Julu, Zaki, Sherif R., Jones, Timothy F., Shieh, Wun-Ju
Publicado no Clin Infect Dis (2017)

Mechanism-Based Screen for G1/S Checkpoint Activators Identifies a Selective Activator of EIF2AK3/PERK Signalling

Por Stockwell, Simon R., Platt, Georgina, Barrie, S. Elaine, Zoumpoulidou, Georgia, te Poele, Robert H., Aherne, G. Wynne, Wilson, Stuart C., Sheldrake, Peter, McDonald, Edward, Venet, Mathilde, Soudy, Christelle, Elustondo, Frédéric, Rigoreau, Laurent, Blagg, Julian, Workman, Paul, Garrett, Michelle D., Mittnacht, Sibylle
Publicado em 2012

A Useful Approach To Identify Novel Small Molecule Inhibitors Of Wnt-Dependent Transcription

Por Ewan, Kenneth, Pająk, Bożena, Stubbs, Mark, Todd, Helen, Barbeau, Olivier, Quevedo, Camilo, Botfield, Hannah, Young, Rodrigo, Ruddle, Ruth, Samuel, Lee, Battersby, Alysia, Raynaud, Florence, Allen, Nicholas, Wilson, Stephen W., Latinkic, Branko, Workman, Paul, McDonald, Edward, Blagg, Julian, Aherne, Wynne, Dale, Trevor
Publicado em 2010

Molecular profiling and combinatorial activity of CCT068127: a potent CDK2 and CDK9 inhibitor

Por Whittaker, Steven R., Barlow, Clare, Martin, Mathew P., Mancusi, Caterina, Wagner, Steve, Self, Annette, Barrie, Elaine, Te Poele, Robert, Sharp, Swee, Brown, Nathan, Wilson, Stuart, Jackson, Wayne, Fischer, Peter M., Clarke, Paul A., Walton, Michael I., McDonald, Edward, Blagg, Julian, Noble, Martin, Garrett, Michelle D., Workman, Paul
Publicado no Mol Oncol (2018)

Biological properties of potent inhibitors of class I phosphatidylinositide 3-kinases: from PI-103 through PI-540, PI-620 to the oral agent GDC-0941

Por Raynaud, Florence I., Eccles, Suzanne A., Patel, Sonal, Alix, Sonia, Box, Gary, Chuckowree, Irina, Folkes, Adrian, Gowan, Sharon, De Haven Brandon, Alexis, Di Stefano, Francesca, Hayes, Angela, Henley, Alan T., Lensun, Letitia, Pergl-Wilson, Giles, Robson, Anthony, Saghir, Nahid, Zhyvoloup, Alexander, McDonald, Edward, Sheldrake, Peter, Shuttleworth, Stephen, Valenti, Melanie, Wan, Nan Chi, Clarke, Paul A., Workman, Paul
Publicado em 2009