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Functional characterization of a novel somatic oncogenic mutation of PIK3CB
Class I phosphoinositide 3-kinase (PI3K) enzymes have attracted considerable attention as drug targets in cancer therapy over the last 20 years. The signaling pathway triggered by class I PI3Ks is dysregulated in a range of tumor types, impacting cell proliferation, survival and apoptosis. Frequent...
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| Publicado no: | Signal Transduct Target Ther |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5740215/ https://ncbi.nlm.nih.gov/pubmed/29279775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sigtrans.2017.63 |
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