Blood and immune cell engineering: Cytoskeletal contractility and nuclear rheology impact cell lineage and localization

Por Shin, Jae-Won, Discher, Dennis E.
Publicado no Bioessays (2015)

Extracellular matrix stiffness causes systematic variations in proliferation and chemosensitivity in myeloid leukemias

Por Shin, Jae-Won, Mooney, David J.
Publicado no Proc Natl Acad Sci U S A (2016)

Improving Stem Cell Therapeutics with Mechanobiology

Por Shin, Jae-Won, Mooney, David J.
Publicado no Cell Stem Cell (2016)

Matrix elasticity in vitro controls muscle stem cell fate in vivo

Por Raab, Matthew, Shin, Jae-Won, Discher, Dennis E
Publicado em 2010

Effects of substrate stiffness and cell-cell contact on mesenchymal stem cell differentiation

Por Mao, Angelo S., Shin, Jae-Won, Mooney, David J.
Publicado no Biomaterials (2016)

Significance of Follow-up in Detection of Pulmonary Metastasis of Colorectal Cancer

Por Shin, Jae Won, Lee, Sun Il, Moon, Hong Young
Publicado em 2010

Myosin-II inhibition and soft 2D matrix maximize multinucleation and cellular projections typical of platelet-producing megakaryocytes

Por Shin, Jae-Won, Swift, Joe, Spinler, Kyle R., Discher, Dennis E.
Publicado em 2011

Stem cell mechanobiology: diverse lessons from bone marrow

Por Ivanovska, Irena L., Shin, Jae-Won, Swift, Joe, Discher, Dennis E.
Publicado no Trends Cell Biol (2015)

Myosin-II repression favors pre/proplatelets but shear activation generates platelets and fails in macrothrombocytopenia

Por Spinler, Kyle R., Shin, Jae-Won, Lambert, Michele P., Discher, Dennis E.
Publicado no Blood (2015)

Mechanobiology of bone marrow stem cells: from myosin-II forces to compliance of matrix and nucleus

Por Shin, Jae-Won, Swift, Joe, Ivanovska, Irena, Spinler, Kyle R., Buxboim, Amnon, Discher, Dennis E.
Publicado em 2013

Lamins regulate cell trafficking and lineage maturation of adult human hematopoietic cells

Por Shin, Jae-Won, Spinler, Kyle R., Swift, Joe, Chasis, Joel A., Mohandas, Narla, Discher, Dennis E.
Publicado em 2013

Coordinated increase of nuclear tension and lamin-A with matrix stiffness outcompetes lamin-B receptor that favors soft tissue phenotypes

Por Buxboim, Amnon, Irianto, Jerome, Swift, Joe, Athirasala, Avathamsa, Shin, Jae-Won, Rehfeldt, Florian, Discher, Dennis E.
Publicado no Mol Biol Cell (2017)

Crawling from soft to stiff matrix polarizes the cytoskeleton and phosphoregulates myosin-II heavy chain

Por Raab, Matthew, Swift, Joe, P. Dingal, P.C. Dave, Shah, Palak, Shin, Jae-Won, Discher, Dennis E.
Publicado em 2012

Label-free mass spectrometry exploits dozens of detected peptides to quantify lamins in wildtype and knockdown cells

Por Swift, Joe, Harada, Takamasa, Buxboim, Amnon, Shin, Jae-Won, Tang, Hsin-Yao, Speicher, David W, Discher, Dennis E
Publicado em 2013

Impact of laparoscopic experience on virtual robotic simulator dexterity

Por Yoo, Byung Eun, Kim, Jin, Cho, Jae Sung, Shin, Jae Won, Lee, Dong Won, Kwak, Jung Myun, Kim, Seon Hahn
Publicado no J Minim Access Surg (2015)

Experience and pharmacokinetics of Levetiracetam in Korean neonates with neonatal seizures

Por Shin, Jae Won, Jung, Yun Seob, Park, Kyungsoo, Lee, Soon Min, Eun, Ho Seon, Park, Min Soo, Park, Kook In, Namgung, Ran
Publicado no Korean J Pediatr (2017)

Deterministic encapsulation of single cells in thin tunable microgels for niche modeling and therapeutic delivery

Por Mao, Angelo S., Shin, Jae-Won, Utech, Stefanie, Wang, Huanan, Uzun, Oktay, Li, Weiwei, Cooper, Madeline, Hu, Yuebi, Zhang, Liyuan, Weitz, David A., Mooney, David J.
Publicado no Nat Mater (2016)

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival

Por Harada, Takamasa, Swift, Joe, Irianto, Jerome, Shin, Jae-Won, Spinler, Kyle R., Athirasala, Avathamsa, Diegmiller, Rocky, Dingal, P.C. Dave P., Ivanovska, Irena L., Discher, Dennis E.
Publicado em 2014

How Long Does Antimycobacterial Antibiotic-loaded Bone Cement Have In Vitro Activity for Musculoskeletal Tuberculosis?

Por Lee, Jae Hoo, Han, Chang Dong, Cho, Sang-Nae, Yang, Ick Hwan, Lee, Woo Suk, Baek, Seung-Hun, Shin, Jae Won, Husein, Khalid Elfadil Ibrahim, Park, Kwan Kyu
Publicado no Clin Orthop Relat Res (2017)

RhoA Is Essential for Maintaining Normal Megakaryocyte Ploidy and Platelet Generation

Por Suzuki, Aae, Shin, Jae-Won, Wang, Yuhuan, Min, Sang H., Poncz, Morty, Choi, John K., Discher, Dennis E., Carpenter, Chris L., Lian, Lurong, Zhao, Liang, Wang, Yangfeng, Abrams, Charles S.
Publicado em 2013