Pharmacokinetics, Pharmacodynamics, and Tolerability of Concomitant Administration of Verinurad and Febuxostat in Healthy Male Volunteers

by Hall, Jesse, Gillen, Michael, Yang, Xiaojuan, Shen, Zancong
Published in Clin Pharmacol Drug Dev (2018)

Paclitaxel Tumor-Priming Enhances siRNA Delivery and Transfection in 3-Dimensional Tumor Cultures

by Wong, Ho Lun, Shen, Zancong, Lu, Ze, Wientjes, M. Guillaume, Au, Jessie L.-S.
Published 2011

In Vitro and In Vivo Interaction Studies Between Lesinurad, a Selective Urate Reabsorption Inhibitor, and Major Liver or Kidney Transporters

by Shen, Zancong, Yeh, Li-Tain, Wallach, Kathleen, Zhu, Nanqun, Kerr, Brad, Gillen, Michael
Published in Clin Drug Investig (2016)

Effects of renal function on pharmacokinetics and pharmacodynamics of lesinurad in adult volunteers

by Gillen, Michael, Valdez, Shakti, Zhou, Dongmei, Kerr, Bradley, Lee, Caroline A, Shen, Zancong
Published in Drug Des Devel Ther (2016)

The Effect of Lesinurad in Combination With Allopurinol on Serum Uric Acid Levels in Patients With Gout

by Baumgartner, Scott, Yeh, Li‐Tain, Shen, Zancong, Kerr, Bradley, Manhard, Kimberly, Quart, Barry
Published in J Clin Pharmacol (2018)

Intravesical Treatments of Bladder Cancer: Review

by Shen, Zancong, Shen, Tong, Wientjes, M. Guillaume, O’Donnell, Michael A., Au, Jessie L.-S.
Published 2008

Pharmacokinetics, pharmacodynamics, and tolerability of verinurad, a selective uric acid reabsorption inhibitor, in healthy adult male subjects

by Shen, Zancong, Gillen, Michael, Miner, Jeffrey N, Bucci, Gail, Wilson, David M, Hall, Jesse W
Published in Drug Des Devel Ther (2017)

Pharmacokinetics, pharmacodynamics, and tolerability of verinurad, a selective uric acid reabsorption inhibitor, in healthy Japanese and non-Asian male subjects

by Hall, Jesse, Gillen, Michael, Liu, Sha, Miner, Jeffrey N, Valdez, Shakti, Shen, Zancong, Lee, Caroline
Published in Drug Des Devel Ther (2018)

Predictive Models of Diffusive Nanoparticle Transport in 3-Dimensional Tumor Cell Spheroids

by Gao, Yue, Li, Mingguang, Chen, Bin, Shen, Zancong, Guo, Peng, Wientjes, M. Guillaume, Au, Jessie L.-S.
Published 2013

Verinurad combined with febuxostat in Japanese adults with gout or asymptomatic hyperuricaemia: a phase 2a, open-label study

by Shiramoto, Masanari, Liu, Sha, Shen, Zancong, Yan, Xiaohong, Yamamoto, Amy, Gillen, Michael, Ito, Yasushi, Hall, Jesse
Published in Rheumatology (Oxford) (2018)

Pharmacokinetics, pharmacodynamics, and safety of lesinurad, a selective uric acid reabsorption inhibitor, in healthy adult males

by Shen, Zancong, Rowlings, Colin, Kerr, Brad, Hingorani, Vijay, Manhard, Kimberly, Quart, Barry, Yeh, Li-Tain, Storgard, Chris
Published in Drug Des Devel Ther (2015)

Supratherapeutic dose evaluation and effect of lesinurad on cardiac repolarization: a thorough QT/QTc study

by Shen, Zancong, Gillen, Michael, Tieu, Kathy, Nguyen, Mai, Harmon, Erin, Wilson, David M, Kerr, Bradley, Lee, Caroline A
Published in Drug Des Devel Ther (2016)

Pharmacodynamic and pharmacokinetic effects and safety of verinurad in combination with allopurinol in adults with gout: a phase IIa, open-label study

by Fleischmann, Roy, Winkle, Peter, Miner, Jeffrey N, Yan, Xiaohong, Hicks, Liz, Valdez, Shakti, Hall, Jesse, Liu, Sha, Shen, Zancong, Gillen, Michael, Hernandez-Illas, Martha
Published in RMD Open (2018)

Pharmacokinetics, Pharmacodynamics, and Tolerability of Concomitant Multiple Dose Administration of Verinurad (RDEA3170) and Allopurinol in Adult Male Subjects With Gout

by Kankam, Martin, Hall, Jesse, Gillen, Michael, Yang, Xiaojuan, Shen, Zancong, Lee, Caroline, Liu, Sha, Miner, Jeffrey N., Walker, Susan, Clauson, Vicki, Wilson, David, Nguyen, Mai
Published in J Clin Pharmacol (2018)

Phase 2a Randomized Controlled Trial of Short-Term Activity, Safety, and Pharmacokinetics of a Novel Nonnucleoside Reverse Transcriptase Inhibitor, RDEA806, in HIV-1-Positive, Anti...

by Moyle, Graeme, Boffito, Marta, Stoehr, Albrecht, Rieger, Armin, Shen, Zancong, Manhard, Kimberly, Sheedy, Beth, Hingorani, Vijay, Raney, Anneke, Nguyen, Mai, Nguyen, Tranh, Ong, Voon, Yeh, Li-Tain, Quart, Barry
Published 2010

Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney

by Miner, Jeffrey, Tan, Philip K., Hyndman, David, Liu, Sha, Iverson, Cory, Nanavati, Payal, Hagerty, David T., Manhard, Kimberly, Shen, Zancong, Girardet, Jean-Luc, Yeh, Li-Tain, Terkeltaub, Robert, Quart, Barry
Published in Arthritis Res Ther (2016)

Effect of Renal Impairment on the Pharmacokinetics and Pharmacodynamics of Verinurad, a Selective Uric Acid Reabsorption Inhibitor

by Smith, William B., Hall, Jesse, Berg, Jolene K., Kazimir, Michal, Yamamoto, Amy, Walker, Susan, Lee, Caroline A., Shen, Zancong, Wilson, David M., Zhou, Dongmei, Gillen, Michael, Marbury, Thomas C.
Published in Clin Drug Investig (2018)

Erratum to: Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney

by Miner, Jeffrey N., Tan, Philip K., Hyndman, David, Liu, Sha, Iverson, Cory, Nanavati, Payal, Hagerty, David T., Manhard, Kimberly, Shen, Zancong, Girardet, Jean-Luc, Yeh, Li-Tain, Terkeltaub, Robert, Quart, Barry
Published in Arthritis Res Ther (2016)

A Phase I Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Combination Therapy with Refametinib plus Sorafenib in Patients with Advanced Cancer

by Adjei, Alex A., Richards, Donald A., El-Khoueiry, Anthony, Braiteh, Fadi, Becerra, Carlos H.R., Stephenson, Joe J., Hezel, Aram F., Sherman, Morris, Garbo, Lawrence, Leffingwell, Diane P., Iverson, Cory, Miner, Jeffrey N., Shen, Zancong, Yeh, Li-Tain, Gunawan, Sonny, Wilson, David M., Manhard, Kimberly J., Rajagopalan, Prabhu, Krissel, Heiko, Clendeninn, Neil J.
Published in Clin Cancer Res (2015)