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Effects of renal function on pharmacokinetics and pharmacodynamics of lesinurad in adult volunteers
INTRODUCTION: Lesinurad is a selective uric acid reabsorption inhibitor approved for the treatment of gout in combination with a xanthine oxidase inhibitor (XOI) in patients who have not achieved target serum uric acid (sUA) levels with an XOI alone. Most people with gout have chronic kidney disease...
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| Publicado no: | Drug Des Devel Ther |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5098526/ https://ncbi.nlm.nih.gov/pubmed/27843295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S119944 |
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