Hippo Pathway and YAP Signaling Alterations in Squamous Cancer of the Head and Neck

Por Santos-de-Frutos, Karla, Segrelles, Carmen, Lorz, Corina
Publicado no J Clin Med (2019)

Inhibition of Protein Kinase B (PKB) and PKCζ Mediates Keratin K10-Induced Cell Cycle Arrest

Por Paramio, Jesus M., Segrelles, Carmen, Ruiz, Sergio, Jorcano, José L.
Publicado em 2001

Establishment of a murine epidermal cell line suitable for in vitro and in vivo skin modelling

Por Segrelles, Carmen, Holguín, Almudena, Hernández, Pilar, Ariza, José M, Paramio, Jesús M, Lorz, Corina
Publicado em 2011

Modulation of Cell Proliferation by Cytokeratins K10 and K16

Por Paramio, Jesús M., Casanova, M. Llanos, Segrelles, Carmen, Mittnacht, Sybille, Lane, E. Birgitte, Jorcano, José L.
Publicado em 1999

The Thyroid Hormone Receptors Modulate the Skin Response to Retinoids

Por García-Serrano, Laura, Gomez-Ferrería, María Ana, Contreras-Jurado, Constanza, Segrelles, Carmen, Paramio, Jesus M., Aranda, Ana
Publicado em 2011

Bosutinib Inhibits EGFR Activation in Head and Neck Cancer

Por Segrelles, Carmen, Contreras, David, Navarro, Elena M., Gutiérrez-Muñoz, Carmen, García-Escudero, Ramón, Paramio, Jesús M., Lorz, Corina
Publicado no Int J Mol Sci (2018)

A Novel Tumor suppressor network in squamous malignancies

Por Costa, Clotilde, Santos, Mirentxu, Segrelles, Carmen, Dueñas, Marta, Lara, M. Fernanda, Agirre, Xabier, Prosper, Felipe, García-Escudero, Ramón, Paramio, Jesús M.
Publicado em 2012

The downregulation of ΔNp63 in p53-deficient mouse epidermal tumors favors metastatic behavior

Por Bornachea, Olga, López-Calderón, Fernando F., Dueñas, Marta, Segrelles, Carmen, Lorz, Corina, Suárez-Cabrera, Cristian, Marañón, María, Paradela-Dobarro, Beatriz, Santos, Mirentxu, Paramio, Jesús M.
Publicado no Oncotarget (2015)

Gene expression profiling of mouse p53-deficient epidermal carcinoma defines molecular determinants of human cancer malignancy

Por García-Escudero, Ramón, Martínez-Cruz, Ana B, Santos, Mirentxu, Lorz, Corina, Segrelles, Carmen, Garaulet, Guillermo, Saiz-Ladera, Cristina, Costa, Clotilde, Buitrago-Pérez, Águeda, Dueñas, Marta, Paramio, Jesús M
Publicado em 2010

p21 suppresses inflammation and tumorigenesis on pRB-deficient stratified epithelia

Por Saiz-Ladera, Cristina, Lara, María Fernanda, Garín, Marina, Ruiz, Sergio, Santos, Mirentxu, Lorz, Corina, García-Escudero, Ramón, Martínez-Fernández, Mónica, Bravo, Ana, Fernández-Capetillo, Oscar, Segrelles, Carmen, Paramio, Jesús M
Publicado no Oncogene (2013)

Differential Role of the RasGEFs Sos1 and Sos2 in Mouse Skin Homeostasis and Carcinogenesis

Por Liceras-Boillos, Pilar, Jimeno, David, García-Navas, Rósula, Lorenzo-Martín, L. Francisco, Menacho-Marquez, Mauricio, Segrelles, Carmen, Gómez, Carmela, Calzada, Nuria, Fuentes-Mateos, Rocío, Paramio, Jesús M., Bustelo, Xosé R., Baltanás, Fernando C., Santos, Eugenio
Publicado no Mol Cell Biol (2018)

A Functional Role of RB-Dependent Pathway in the Control of Quiescence in Adult Epidermal Stem Cells Revealed by Genomic Profiling

Por Lorz, Corina, García-Escudero, Ramón, Segrelles, Carmen, Garín, Marina I., Ariza, José M., Santos, Mirentxu, Ruiz, Sergio, Lara, María F., Martínez-Cruz, Ana B., Costa, Clotilde, Buitrago-Pérez, Águeda, Saiz-Ladera, Cristina, Dueñas, Marta, Paramio, Jesús M.
Publicado em 2010

Constitutively Active Akt Induces Ectodermal Defects and Impaired Bone Morphogenetic Protein Signaling

Por Segrelles, Carmen, Moral, Marta, Lorz, Corina, Santos, Mirentxu, Lu, Jerry, Cascallana, José Luis, Lara, M. Fernanda, Carbajal, Steve, Martínez-Cruz, Ana Belén, García-Escudero, Ramón, Beltran, Linda, Segovia, José C., Bravo, Ana, DiGiovanni, John, Paramio, Jesús M.
Publicado em 2008

Inefficient differentiation response to cell cycle stress leads to genomic instability and malignant progression of squamous carcinoma cells

Por Alonso-Lecue, Pilar, de Pedro, Isabel, Coulon, Vincent, Molinuevo, Rut, Lorz, Corina, Segrelles, Carmen, Ceballos, Laura, López-Aventín, Daniel, García-Valtuille, Ana, Bernal, José M, Mazorra, Francisco, Pujol, Ramón M, Paramio, Jesús, Ramón Sanz, J, Freije, Ana, Toll, Agustí, Gandarillas, Alberto
Publicado no Cell Death Dis (2017)

EMT and induction of miR-21 mediate metastasis development in Trp53-deficient tumours

Por Bornachea, Olga, Santos, Mirentxu, Martínez-Cruz, Ana Belén, García-Escudero, Ramón, Dueñas, Marta, Costa, Clotilde, Segrelles, Carmen, Lorz, Corina, Buitrago, Agueda, Saiz-Ladera, Cristina, Agirre, Xabier, Grande, Teresa, Paradela, Beatriz, Maraver, Antonio, Ariza, José M., Prosper, Felipe, Serrano, Manuel, Sánchez-Céspedes, Montse, Paramio, Jesús M.
Publicado em 2012

Transgenic Mice Expressing Constitutively Active Akt in Oral Epithelium Validate Klf4 as a Potential Biomarker of Head and Neck Squamous Cell Carcinoma

Por Moral, Marta, Segrelles, Carmen, Martínez-Cruz, Ana Belén, Lorz, Corina, Santos, Mirentxu, García-Escudero, Ramón, Lu, Jerry, Buitrago, Agueda, Costa, Clotilde, Saiz, Cristina, Ariza, José M., Dueñas, Marta, Rodriguez-Peralto, Jose L, Martinez-Tello, Francisco J, Rodriguez-Pinilla, Maria, Sanchez-Cespedes, Montserrat, DiGiovanni, John, Paramio, Jesús M.
Publicado em 2009

Akt activation synergizes with Trp53 loss in oral epithelium to produce a novel mouse model for head and neck squamous cell carcinoma

Por Moral, Marta, Segrelles, Carmen, Lara, M. Fernanda, Martinez-Cruz, Ana Belen, Lorz, Corina, Santos, Mirentxu, Garcia-Escudero, Ramon, Lu, Jerry, Kiguchi, Kaoru, Buitrago, Agueda, Costa, Clotilde, Saiz, Cristina, Rodriguez-Peralto, Jose L, Martinez-Tello, Francisco J, Rodriguez-Pinilla, Maria, Sanchez-Cespedes, Montserrat, Garin, Marina, Grande, Teresa, Bravo, Ana, DiGiovanni, John, Paramio, Jesus M.
Publicado em 2009

VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma

Por Lorenzo-Martín, L. Francisco, Fernández-Parejo, Natalia, Menacho-Márquez, Mauricio, Rodríguez-Fdez, Sonia, Robles-Valero, Javier, Zumalave, Sonia, Fabbiano, Salvatore, Pascual, Gloria, García-Pedrero, Juana M., Abad, Antonio, García-Macías, María C., González, Nazareno, Lorenzano-Menna, Pablo, Pavón, Miguel A., González-Sarmiento, Rogelio, Segrelles, Carmen, Paramio, Jesús M., Tubío, José M. C., Rodrigo, Juan P., Benitah, Salvador A., Cuadrado, Myriam, Bustelo, Xosé R.
Publicado no Nat Commun (2020)