New models of large-cell neuroendocrine carcinoma and small-cell lung carcinoma

Por Santos, Mirentxu
Publicado no Mol Cell Oncol (2020)

Skin Tumors Rb(eing) Uncovered

Por Costa, Clotilde, Paramio, Jesús M., Santos, Mirentxu
Publicado em 2013

Development and long-term evaluation of a new (68)Ge/(68)Ga generator based on nano-SnO(2) for PET imaging

Por Romero, Eduardo, Martínez, Alfonso, Oteo, Marta, Ibañez, Marta, Santos, Mirentxu, Morcillo, Miguel Ángel
Publicado no Sci Rep (2020)

Deregulation of the pRb-E2F4 axis alters epidermal homeostasis and favors tumor development

Por Costa, Clotilde, Santos, Mirentxu, Martínez-Fernández, Mónica, Lorz, Corina, Lázaro, Sara, Paramio, Jesús M.
Publicado no Oncotarget (2016)

Correction: Deregulation of the pRb-E2F4 axis alters epidermal homeostasis and favors tumor development

Por Costa, Clotilde, Santos, Mirentxu, Martínez-Fernández, Mónica, Lorz, Corina, Lázaro, Sara, Paramio, Jesús M.
Publicado no Oncotarget (2017)

A Novel Tumor suppressor network in squamous malignancies

Por Costa, Clotilde, Santos, Mirentxu, Segrelles, Carmen, Dueñas, Marta, Lara, M. Fernanda, Agirre, Xabier, Prosper, Felipe, García-Escudero, Ramón, Paramio, Jesús M.
Publicado em 2012

Ablating all three retinoblastoma family members in mouse lung leads to neuroendocrine tumor formation

Por Lázaro, Sara, Pérez-Crespo, Miriam, Enguita, Ana Belén, Hernández, Pilar, Martínez-Palacio, Jesús, Oteo, Marta, Sage, Julien, Paramio, Jesús M., Santos, Mirentxu
Publicado no Oncotarget (2016)

Correction: Ablating all three retinoblastoma family members in mouse lung leads to neuroendocrine tumor formation

Por Lázaro, Sara, Pérez-Crespo, Miriam, Enguita, Ana Belén, Hernández, Pilar, Martínez-Palacio, Jesús, Oteo, Marta, Sage, Julien, Paramio, Jesús M., Santos, Mirentxu
Publicado no Oncotarget (2017)

The downregulation of ΔNp63 in p53-deficient mouse epidermal tumors favors metastatic behavior

Por Bornachea, Olga, López-Calderón, Fernando F., Dueñas, Marta, Segrelles, Carmen, Lorz, Corina, Suárez-Cabrera, Cristian, Marañón, María, Paradela-Dobarro, Beatriz, Santos, Mirentxu, Paramio, Jesús M.
Publicado no Oncotarget (2015)

Gene expression profiling of mouse p53-deficient epidermal carcinoma defines molecular determinants of human cancer malignancy

Por García-Escudero, Ramón, Martínez-Cruz, Ana B, Santos, Mirentxu, Lorz, Corina, Segrelles, Carmen, Garaulet, Guillermo, Saiz-Ladera, Cristina, Costa, Clotilde, Buitrago-Pérez, Águeda, Dueñas, Marta, Paramio, Jesús M
Publicado em 2010

Differential development of large-cell neuroendocrine or small-cell lung carcinoma upon inactivation of 4 tumor suppressor genes

Por Lázaro, Sara, Pérez-Crespo, Miriam, Lorz, Corina, Bernardini, Alejandra, Oteo, Marta, Enguita, Ana Belén, Romero, Eduardo, Hernández, Pilar, Tomás, Laura, Morcillo, Miguel Ángel, Paramio, Jesús M., Santos, Mirentxu
Publicado no Proc Natl Acad Sci U S A (2019)

p21 suppresses inflammation and tumorigenesis on pRB-deficient stratified epithelia

Por Saiz-Ladera, Cristina, Lara, María Fernanda, Garín, Marina, Ruiz, Sergio, Santos, Mirentxu, Lorz, Corina, García-Escudero, Ramón, Martínez-Fernández, Mónica, Bravo, Ana, Fernández-Capetillo, Oscar, Segrelles, Carmen, Paramio, Jesús M
Publicado no Oncogene (2013)

A Functional Role of RB-Dependent Pathway in the Control of Quiescence in Adult Epidermal Stem Cells Revealed by Genomic Profiling

Por Lorz, Corina, García-Escudero, Ramón, Segrelles, Carmen, Garín, Marina I., Ariza, José M., Santos, Mirentxu, Ruiz, Sergio, Lara, María F., Martínez-Cruz, Ana B., Costa, Clotilde, Buitrago-Pérez, Águeda, Saiz-Ladera, Cristina, Dueñas, Marta, Paramio, Jesús M.
Publicado em 2010

Constitutively Active Akt Induces Ectodermal Defects and Impaired Bone Morphogenetic Protein Signaling

Por Segrelles, Carmen, Moral, Marta, Lorz, Corina, Santos, Mirentxu, Lu, Jerry, Cascallana, José Luis, Lara, M. Fernanda, Carbajal, Steve, Martínez-Cruz, Ana Belén, García-Escudero, Ramón, Beltran, Linda, Segovia, José C., Bravo, Ana, DiGiovanni, John, Paramio, Jesús M.
Publicado em 2008

Mouse p53-Deficient Cancer Models as Platforms for Obtaining Genomic Predictors of Human Cancer Clinical Outcomes

Por Dueñas, Marta, Santos, Mirentxu, Aranda, Juan F., Bielza, Concha, Martínez-Cruz, Ana B., Lorz, Corina, Taron, Miquel, Ciruelos, Eva M., Rodríguez-Peralto, José L., Martín, Miguel, Larrañaga, Pedro, Dahabreh, Jubrail, Stathopoulos, George P., Rosell, Rafael, Paramio, Jesús M., García-Escudero, Ramón
Publicado em 2012

EMT and induction of miR-21 mediate metastasis development in Trp53-deficient tumours

Por Bornachea, Olga, Santos, Mirentxu, Martínez-Cruz, Ana Belén, García-Escudero, Ramón, Dueñas, Marta, Costa, Clotilde, Segrelles, Carmen, Lorz, Corina, Buitrago, Agueda, Saiz-Ladera, Cristina, Agirre, Xabier, Grande, Teresa, Paradela, Beatriz, Maraver, Antonio, Ariza, José M., Prosper, Felipe, Serrano, Manuel, Sánchez-Céspedes, Montse, Paramio, Jesús M.
Publicado em 2012

Transgenic Mice Expressing Constitutively Active Akt in Oral Epithelium Validate Klf4 as a Potential Biomarker of Head and Neck Squamous Cell Carcinoma

Por Moral, Marta, Segrelles, Carmen, Martínez-Cruz, Ana Belén, Lorz, Corina, Santos, Mirentxu, García-Escudero, Ramón, Lu, Jerry, Buitrago, Agueda, Costa, Clotilde, Saiz, Cristina, Ariza, José M., Dueñas, Marta, Rodriguez-Peralto, Jose L, Martinez-Tello, Francisco J, Rodriguez-Pinilla, Maria, Sanchez-Cespedes, Montserrat, DiGiovanni, John, Paramio, Jesús M.
Publicado em 2009

Akt activation synergizes with Trp53 loss in oral epithelium to produce a novel mouse model for head and neck squamous cell carcinoma

Por Moral, Marta, Segrelles, Carmen, Lara, M. Fernanda, Martinez-Cruz, Ana Belen, Lorz, Corina, Santos, Mirentxu, Garcia-Escudero, Ramon, Lu, Jerry, Kiguchi, Kaoru, Buitrago, Agueda, Costa, Clotilde, Saiz, Cristina, Rodriguez-Peralto, Jose L, Martinez-Tello, Francisco J, Rodriguez-Pinilla, Maria, Sanchez-Cespedes, Montserrat, Garin, Marina, Grande, Teresa, Bravo, Ana, DiGiovanni, John, Paramio, Jesus M.
Publicado em 2009

In vivo disruption of an Rb-E2F-Ezh2 signaling loop causes bladder cancer

Por Santos, Mirentxu, Martínez-Fernández, Mónica, Dueñas, Marta, García-Escudero, Ramón, Alfaya, Begoña, Villacampa, Felipe, Saiz-Ladera, Cristina, Costa, Clotilde, Oteo, Marta, Duarte, José, Martínez, Victor, Gómez-Rodriguez, Mª José, Martín, Mª Luisa, Fernández, Manoli, Viatour, Patrick, Morcillo, Miguel A, Sage, Julien, Castellano, Daniel, Rodriguez-Peralto, Jose L, de la Rosa, Federico, Paramio, Jesús M
Publicado no Cancer Res (2014)