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p21 suppresses inflammation and tumorigenesis on pRB-deficient stratified epithelia
The retinoblastoma gene product (pRb) controls proliferation and differentiation processes in stratified epithelia. Importantly, an in contrast to other tissues, Rb deficiency does not lead to spontaneous skin tumor formation. As the cyclin dependent kinase inhibitor p21 regulates proliferation and...
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| Publicado no: | Oncogene |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4913869/ https://ncbi.nlm.nih.gov/pubmed/24121270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.417 |
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