Remodeling of Human Osteochondral Defects via rAAV-Mediated Co-Overexpression of TGF-β and IGF-I from Implanted Human Bone Marrow-Derived Mesenchymal Stromal Cells

Por Morscheid, Stephanie, Venkatesan, Jagadeesh Kumar, Rey-Rico, Ana, Schmitt, Gertrud, Cucchiarini, Magali
Publicado no J Clin Med (2019)

SOX9 gene transfer via safe, stable, replication-defective recombinant adeno-associated virus vectors as a novel, powerful tool to enhance the chondrogenic potential of human mesen...

Por Venkatesan, Jagadeesh K, Ekici, Myriam, Madry, Henning, Schmitt, Gertrud, Kohn, Dieter, Cucchiarini, Magali
Publicado em 2012

rAAV-mediated overexpression of TGF-β stably restructures human osteoarthritic articular cartilage in situ

Por Venkatesan, Jagadeesh K, Rey-Rico, Ana, Schmitt, Gertrud, Wezel, Anna, Madry, Henning, Cucchiarini, Magali
Publicado em 2013

Influence of insulin-like growth factor I overexpression via recombinant adeno-associated vector gene transfer upon the biological activities and differentiation potential of human...

Por Frisch, Janina, Venkatesan, Jagadeesh Kumar, Rey-Rico, Ana, Schmitt, Gertrud, Madry, Henning, Cucchiarini, Magali
Publicado em 2014

Chondrogenic Differentiation Processes in Human Bone Marrow Aspirates upon rAAV-Mediated Gene Transfer and Overexpression of the Insulin-Like Growth Factor I

Por Frisch, Janina, Rey-Rico, Ana, Venkatesan, Jagadeesh Kumar, Schmitt, Gertrud, Madry, Henning, Cucchiarini, Magali
Publicado no Tissue Eng Part A (2015)

TGF‐β gene transfer and overexpression via rAAV vectors stimulates chondrogenic events in human bone marrow aspirates

Por Frisch, Janina, Rey‐Rico, Ana, Venkatesan, Jagadeesh Kumar, Schmitt, Gertrud, Madry, Henning, Cucchiarini, Magali
Publicado no J Cell Mol Med (2016)

Impact of mechanical stimulation on the chondrogenic processes in human bone marrow aspirates modified to overexpress sox9 via rAAV vectors

Por Venkatesan, Jagadeesh K., Frisch, Janina, Rey-Rico, Ana, Schmitt, Gertrud, Madry, Henning, Cucchiarini, Magali
Publicado no J Exp Orthop (2017)

Therapeutic Effects of rAAV-Mediated Concomittant Gene Transfer and Overexpression of TGF-β and IGF-I on the Chondrogenesis of Human Bone-Marrow-Derived Mesenchymal Stem Cells

Por Morscheid, Stephanie, Rey-Rico, Ana, Schmitt, Gertrud, Madry, Henning, Cucchiarini, Magali, Venkatesan, Jagadeesh Kumar
Publicado no Int J Mol Sci (2019)

Effects of rAAV-Mediated sox9 Overexpression on the Biological Activities of Human Osteoarthritic Articular Chondrocytes in Their Intrinsic Three-Dimensional Environment

Por Daniels, Oliver, Frisch, Janina, Venkatesan, Jagadeesh K., Rey-Rico, Ana, Schmitt, Gertrud, Cucchiarini, Magali
Publicado no J Clin Med (2019)

rAAV Vectors as Safe and Efficient Tools for the Stable Delivery of Genes to Primary Human Chondrosarcoma Cells In Vitro and In Situ

Por Madry, Henning, Venkatesan, Jagadeesh K., Schmitt, Gertrud, Schetting, Sarah, Ekici, Myriam, Kohn, Dieter, Cucchiarini, Magali
Publicado em 2012

Effects of rAAV-mediated FGF-2 gene transfer and overexpression upon the chondrogenic differentiation processes in human bone marrow aspirates

Por Frisch, Janina, Venkatesan, Jagadeesh K., Rey-Rico, Ana, Zawada, Adam M., Schmitt, Gertrud, Madry, Henning, Cucchiarini, Magali
Publicado no J Exp Orthop (2016)

rAAV-mediated overexpression of TGF-β via vector delivery in polymeric micelles stimulates the biological and reparative activities of human articular chondrocytes in vitro and in...

Por Rey-Rico, Ana, Venkatesan, Jagadeesh K, Schmitt, Gertrud, Concheiro, Angel, Madry, Henning, Alvarez-Lorenzo, Carmen, Cucchiarini, Magali
Publicado no Int J Nanomedicine (2017)

Co-overexpression of TGF-β and SOX9 via rAAV gene transfer modulates the metabolic and chondrogenic activities of human bone marrow-derived mesenchymal stem cells

Por Tao, Ke, Frisch, Janina, Rey-Rico, Ana, Venkatesan, Jagadeesh K., Schmitt, Gertrud, Madry, Henning, Lin, Jianhao, Cucchiarini, Magali
Publicado no Stem Cell Res Ther (2016)

Effects of combined rAAV-mediated TGF-β and sox9 gene transfer and overexpression on the metabolic and chondrogenic activities in human bone marrow aspirates

Por Tao, Ke, Rey-Rico, Ana, Frisch, Janina, Venkatesan, Jagadeesh Kumar, Schmitt, Gertrud, Madry, Henning, Lin, Jianhao, Cucchiarini, Magali
Publicado no J Exp Orthop (2017)

Genetic Modification of Human Peripheral Blood Aspirates Using Recombinant Adeno‐Associated Viral Vectors for Articular Cartilage Repair with a Focus on Chondrogenic Transforming G...

Por Frisch, Janina, Orth, Patrick, Venkatesan, Jagadeesh Kumar, Rey‐Rico, Ana, Schmitt, Gertrud, Kohn, Dieter, Madry, Henning, Cucchiarini, Magali
Publicado no Stem Cells Transl Med (2016)

Peripheral blood aspirates overexpressing IGF‐I via rAAV gene transfer undergo enhanced chondrogenic differentiation processes

Por Frisch, Janina, Orth, Patrick, Rey‐Rico, Ana, Venkatesan, Jagadeesh Kumar, Schmitt, Gertrud, Madry, Henning, Kohn, Dieter, Cucchiarini, Magali
Publicado no J Cell Mol Med (2017)

Chondrogenic Differentiation Processes in Human Bone-Marrow Aspirates Seeded in Three-Dimensional-Woven Poly(ɛ-Caprolactone) Scaffolds Enhanced by Recombinant Adeno-Associated Viru...

Por Venkatesan, Jagadeesh K., Moutos, Franklin T., Rey-Rico, Ana, Estes, Bradley T., Frisch, Janina, Schmitt, Gertrud, Madry, Henning, Guilak, Farshid, Cucchiarini, Magali
Publicado no Hum Gene Ther (2018)

rAAV-Mediated Overexpression of SOX9 and TGF-β via Carbon Dot-Guided Vector Delivery Enhances the Biological Activities in Human Bone Marrow-Derived Mesenchymal Stromal Cells

Por Meng, Weikun, Rey-Rico, Ana, Claudel, Mickaël, Schmitt, Gertrud, Speicher-Mentges, Susanne, Pons, Françoise, Lebeau, Luc, Venkatesan, Jagadeesh K., Cucchiarini, Magali
Publicado no Nanomaterials (Basel) (2020)

Enhanced Chondrogenic Differentiation Activities in Human Bone Marrow Aspirates via sox9 Overexpression Mediated by pNaSS-Grafted PCL Film-Guided rAAV Gene Transfer

Por Venkatesan, Jagadeesh K., Meng, Weikun, Rey-Rico, Ana, Schmitt, Gertrud, Speicher-Mentges, Susanne, Falentin-Daudré, Céline, Leroux, Amélie, Madry, Henning, Migonney, Véronique, Cucchiarini, Magali
Publicado no Pharmaceutics (2020)

Benefits of Recombinant Adeno-Associated Virus (rAAV)-Mediated Insulinlike Growth Factor I (IGF-I) Overexpression for the Long-Term Reconstruction of Human Osteoarthritic Cartilage...

Por Weimer, Anja, Madry, Henning, Venkatesan, Jagadeesh K, Schmitt, Gertrud, Frisch, Janina, Wezel, Anna, Jung, Jochen, Kohn, Dieter, Terwilliger, Ernest F, Trippel, Stephen B, Cucchiarini, Magali
Publicado em 2011