Impact of mechanical stimulation on the chondrogenic processes in human bone marrow aspirates modified to overexpress sox9 via rAAV vectors

BACKGROUND: Evaluation of gene-based approaches to target human bone marrow aspirates in conditions of mechanical stimulation that aim at reproducing the natural joint environment may allow to develop improved treatments for articular cartilage injuries. In the present study, we investigated the pot...

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Détails bibliographiques
Publié dans:J Exp Orthop
Auteurs principaux: Venkatesan, Jagadeesh K., Frisch, Janina, Rey-Rico, Ana, Schmitt, Gertrud, Madry, Henning, Cucchiarini, Magali
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2017
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Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478551/
https://ncbi.nlm.nih.gov/pubmed/28634835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40634-017-0097-1
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