Effects of rAAV-mediated FGF-2 gene transfer and overexpression upon the chondrogenic differentiation processes in human bone marrow aspirates

BACKGROUND: Application of genetically modified bone marrow concentrates in articular cartilage lesions is a promising approach to enhance cartilage repair by stimulating the chondrogenic differentiation processes in sites of injury. METHOD: In the present study, we examined the potential benefits o...

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Bibliografiske detaljer
Udgivet i:J Exp Orthop
Main Authors: Frisch, Janina, Venkatesan, Jagadeesh K., Rey-Rico, Ana, Zawada, Adam M., Schmitt, Gertrud, Madry, Henning, Cucchiarini, Magali
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967065/
https://ncbi.nlm.nih.gov/pubmed/27473203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40634-016-0052-6
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