A Human Challenge Model for Mycobacterium tuberculosis Using Mycobacterium bovis Bacille Calmette-Guérin

Por Minassian, Angela M., Satti, Iman, Poulton, Ian D., Meyer, Joel, Hill, Adrian V. S., McShane, Helen
Publicado em 2012

Gene Expression and Cytokine Profile Correlate With Mycobacterial Growth in a Human BCG Challenge Model

Por Matsumiya, Magali, Satti, Iman, Chomka, Agnieszka, Harris, Stephanie A., Stockdale, Lisa, Meyer, Joel, Fletcher, Helen A., McShane, Helen
Publicado no J Infect Dis (2015)

Assay optimisation and technology transfer for multi-site immuno-monitoring in vaccine trials

Por Smith, Steven G., Harris, Stephanie A., Satti, Iman, Bryan, Donna, Walker, K. Barry, Dockrell, Hazel M., McShane, Helen, Ho, Mei Mei
Publicado no PLoS One (2017)

Evaluation of a Human BCG Challenge Model to Assess Antimycobacterial Immunity Induced by BCG and a Candidate Tuberculosis Vaccine, MVA85A, Alone and in Combination

Por Harris, Stephanie A., Meyer, Joel, Satti, Iman, Marsay, Leanne, Poulton, Ian D., Tanner, Rachel, Minassian, Angela M., Fletcher, Helen A., McShane, Helen
Publicado em 2014

Optimization of a Human Bacille Calmette-Guérin Challenge Model: A Tool to Evaluate Antimycobacterial Immunity

Por Minhinnick, Alice, Harris, Stephanie, Wilkie, Morven, Peter, Jonathan, Stockdale, Lisa, Manjaly-Thomas, Zita-Rose, Vermaak, Samantha, Satti, Iman, Moss, Paul, McShane, Helen
Publicado no J Infect Dis (2016)

Comparing the safety and immunogenicity of a candidate TB vaccine MVA85A administered by intramuscular and intradermal delivery()

Por Meyer, Joel, Harris, Stephanie A., Satti, Iman, Poulton, Ian D., Poyntz, Hazel C., Tanner, Rachel, Rowland, Rosalind, Griffiths, Kristin L., Fletcher, Helen A., McShane, Helen
Publicado no Vaccine (2013)

Safety and immunogenicity of a candidate tuberculosis vaccine MVA85A delivered by aerosol in BCG-vaccinated healthy adults: a phase 1, double-blind, randomised controlled trial

Por Satti, Iman, Meyer, Joel, Harris, Stephanie A, Thomas, Zita-Rose Manjaly, Griffiths, Kristin, Antrobus, Richard D, Rowland, Rosalind, Ramon, Raquel Lopez, Smith, Mary, Sheehan, Sharon, Bettinson, Henry, McShane, Helen
Publicado em 2014

Inflammatory and myeloid-associated gene expression before and one day after infant vaccination with MVA85A correlates with induction of a T cell response

Por Matsumiya, Magali, Harris, Stephanie A, Satti, Iman, Stockdale, Lisa, Tanner, Rachel, O’Shea, Matthew K, Tameris, Michelle, Mahomed, Hassan, Hatherill, Mark, Scriba, Thomas J, Hanekom, Willem A, McShane, Helen, Fletcher, Helen A
Publicado em 2014

Intracellular Cytokine Staining and Flow Cytometry: Considerations for Application in Clinical Trials of Novel Tuberculosis Vaccines

Por Smith, Steven G., Smits, Kaatje, Joosten, Simone A., van Meijgaarden, Krista E., Satti, Iman, Fletcher, Helen A., Caccamo, Nadia, Dieli, Francesco, Mascart, Francoise, McShane, Helen, Dockrell, Hazel M., Ottenhoff, Tom H. M.
Publicado no PLoS One (2015)

The effect of current Schistosoma mansoni infection on the immunogenicity of a candidate TB vaccine, MVA85A, in BCG-vaccinated adolescents: An open-label trial

Por Wajja, Anne, Kizito, Dennison, Nassanga, Beatrice, Nalwoga, Angela, Kabagenyi, Joyce, Kimuda, Simon, Galiwango, Ronald, Mutonyi, Gertrude, Vermaak, Samantha, Satti, Iman, Verweij, Jaco, Tukahebwa, Edridah, Cose, Stephen, Levin, Jonathan, Kaleebu, Pontiano, Elliott, Alison M., McShane, Helen
Publicado no PLoS Negl Trop Dis (2017)

Process of Assay Selection and Optimization for the Study of Case and Control Samples from a Phase IIb Efficacy Trial of a Candidate Tuberculosis Vaccine, MVA85A

Por Harris, Stephanie A., Satti, Iman, Matsumiya, Magali, Stockdale, Lisa, Chomka, Agnieszka, Tanner, Rachel, O'Shea, Matthew K., Manjaly Thomas, Zita-Rose, Tameris, Michele, Mahomed, Hassan, Scriba, Thomas J., Hanekom, Willem A., Fletcher, Helen A., McShane, Helen
Publicado em 2014

A first-in-human phase 1 trial to evaluate the safety and immunogenicity of the candidate tuberculosis vaccine MVA85A-IMX313, administered to BCG-vaccinated adults

Por Minhinnick, Alice, Satti, Iman, Harris, Stephanie, Wilkie, Morven, Sheehan, Sharon, Stockdale, Lisa, Thomas, Zita-Rose Manjaly, Lopez-Ramon, Raquel, Poulton, Ian, Lawrie, Alison, Vermaak, Samantha, Le Vert, Alexandre, Del Campo, Judith, Hill, Fergal, Moss, Paul, McShane, Helen
Publicado no Vaccine (2016)

Inhibition of Mycobacterial Growth In Vitro following Primary but Not Secondary Vaccination with Mycobacterium bovis BCG

Por Fletcher, Helen A., Tanner, Rachel, Wallis, Robert S., Meyer, Joel, Manjaly, Zita-Rose, Harris, Stephanie, Satti, Iman, Silver, Richard F., Hoft, Dan, Kampmann, Beate, Walker, K. Barry, Dockrell, Hazel M., Fruth, Uli, Barker, Lew, Brennan, Michael J., McShane, Helen
Publicado em 2013

A Phase I, Open-Label Trial, Evaluating the Safety and Immunogenicity of Candidate Tuberculosis Vaccines AERAS-402 and MVA85A, Administered by Prime-Boost Regime in BCG-Vaccinated...

Por Sheehan, Sharon, Harris, Stephanie A., Satti, Iman, Hokey, David A., Dheenadhayalan, Veerabadran, Stockdale, Lisa, Manjaly Thomas, Zita-Rose, Minhinnick, Alice, Wilkie, Morven, Vermaak, Samantha, Meyer, Joel, O’Shea, Matthew K., Pau, Maria Grazia, Versteege, Isabella, Douoguih, Macaya, Hendriks, Jenny, Sadoff, Jerald, Landry, Bernard, Moss, Paul, McShane, Helen
Publicado no PLoS One (2015)

Safety, immunogenicity, and efficacy of the candidate tuberculosis vaccine MVA85A in healthy adults infected with HIV-1: a randomised, placebo-controlled, phase 2 trial

Por Ndiaye, Birahim Pierre, Thienemann, Friedrich, Ota, Martin, Landry, Bernard S, Camara, Makhtar, Dièye, Siry, Dieye, Tandakha Ndiaye, Esmail, Hanif, Goliath, Rene, Huygen, Kris, January, Vanessa, Ndiaye, Ibrahima, Oni, Tolu, Raine, Michael, Romano, Marta, Satti, Iman, Sutton, Sharon, Thiam, Aminata, Wilkinson, Katalin A, Mboup, Souleymane, Wilkinson, Robert J, McShane, Helen
Publicado no Lancet Respir Med (2015)

Safety and immunogenicity of an FP9-vectored candidate tuberculosis vaccine (FP85A), alone and with candidate vaccine MVA85A in BCG-vaccinated healthy adults: A phase I clinical tr...

Por Rowland, Rosalind, Pathan, Ansar A., Satti, Iman, Poulton, Ian D., Matsumiya, Magali M. L., Whittaker, Megan, Minassian, Angela M., O’Hara, Geraldine A., Hamill, Matthew, Scott, Janet T., Harris, Stephanie A., Poyntz, Hazel C., Bateman, Cynthia, Meyer, Joel, Williams, Nicola, Gilbert, Sarah C., Lawrie, Alison M., Hill, Adrian V.S., McShane, Helen
Publicado em 2013

A Phase I study evaluating the safety and immunogenicity of MVA85A, a candidate TB vaccine, in HIV-infected adults

Por Minassian, Angela M, Rowland, Rosalind, Beveridge, Natalie E R, Poulton, Ian D, Satti, Iman, Harris, Stephanie, Poyntz, Hazel, Hamill, Matthew, Griffiths, Kristin, Sander, Clare R, Ambrozak, David R, Price, David A, Hill, Brenna J, Casazza, Joseph P, Douek, Daniel C, Koup, Richard A, Roederer, Mario, Winston, Alan, Ross, Jonathan, Sherrard, Jackie, Rooney, Guy, Williams, Nicola, Lawrie, Alison M, Fletcher, Helen A, Pathan, Ansar A, McShane, Helen
Publicado em 2011

T-cell activation is an immune correlate of risk in BCG vaccinated infants

Por Fletcher, Helen A., Snowden, Margaret A., Landry, Bernard, Rida, Wasima, Satti, Iman, Harris, Stephanie A., Matsumiya, Magali, Tanner, Rachel, O'Shea, Matthew K., Dheenadhayalan, Veerabadran, Bogardus, Leah, Stockdale, Lisa, Marsay, Leanne, Chomka, Agnieszka, Harrington-Kandt, Rachel, Manjaly-Thomas, Zita-Rose, Naranbhai, Vivek, Stylianou, Elena, Darboe, Fatoumatta, Penn-Nicholson, Adam, Nemes, Elisa, Hatherill, Mark, Hussey, Gregory, Mahomed, Hassan, Tameris, Michele, McClain, J Bruce, Evans, Thomas G., Hanekom, Willem A., Scriba, Thomas J., McShane, Helen
Publicado no Nat Commun (2016)

Corrigendum: T-cell activation is an immune correlate of risk in BCG vaccinated infants

Por Fletcher, Helen A., Snowden, Margaret A., Landry, Bernard, Rida, Wasima, Satti, Iman, Harris, Stephanie A., Matsumiya, Magali, Tanner, Rachel, O'Shea, Matthew K., Dheenadhayalan, Veerabadran, Bogardus, Leah, Stockdale, Lisa, Marsay, Leanne, Chomka, Agnieszka, Harrington-Kandt, Rachel, Manjaly-Thomas, Zita-Rose, Naranbhai, Vivek, Stylianou, Elena, Darboe, Fatoumatta, Penn-Nicholson, Adam, Nemes, Elisa, Hatherill, Mark, Hussey, Gregory, Mahomed, Hassan, Tameris, Michele, McClain, J. Bruce, Evans, Thomas G., Hanekom, Willem A., Scriba, Thomas J., McShane, Helen
Publicado no Nat Commun (2016)