Comparing the safety and immunogenicity of a candidate TB vaccine MVA85A administered by intramuscular and intradermal delivery()

BACKGROUND: New vaccines to prevent tuberculosis are urgently needed. MVA85A is a novel viral vector TB vaccine candidate designed to boost BCG-induced immunity when delivered intradermally. To date, intramuscular delivery has not been evaluated. Skin and muscle have distinct anatomical and immunolo...

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Publicado no:Vaccine
Main Authors: Meyer, Joel, Harris, Stephanie A., Satti, Iman, Poulton, Ian D., Poyntz, Hazel C., Tanner, Rachel, Rowland, Rosalind, Griffiths, Kristin L., Fletcher, Helen A., McShane, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405058/
https://ncbi.nlm.nih.gov/pubmed/23266342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.12.042
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