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Gene Expression and Cytokine Profile Correlate With Mycobacterial Growth in a Human BCG Challenge Model

Background. Bacillus Calmette-Guerin (BCG) vaccine is the most widely administered vaccine in the world, yet its mechanism of action remains unclear. We hypothesize that certain immune pathways are associated with reduced mycobacterial growth following BCG challenge in human volunteers. Methods. We...

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Bibliographische Detailangaben
Veröffentlicht in:J Infect Dis
Hauptverfasser: Matsumiya, Magali, Satti, Iman, Chomka, Agnieszka, Harris, Stephanie A., Stockdale, Lisa, Meyer, Joel, Fletcher, Helen A., McShane, Helen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392868/
https://ncbi.nlm.nih.gov/pubmed/25381367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu615
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