A first-in-human phase 1 trial to evaluate the safety and immunogenicity of the candidate tuberculosis vaccine MVA85A-IMX313, administered to BCG-vaccinated adults

INTRODUCTION: There is an urgent need for a new and effective tuberculosis vaccine because BCG does not sufficiently prevent pulmonary disease. IMX313 is a novel carrier protein designed to improve cellular and humoral immunity. MVA85A-IMX313 is a novel vaccine candidate designed to boost immunity p...

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Publicado no:Vaccine
Main Authors: Minhinnick, Alice, Satti, Iman, Harris, Stephanie, Wilkie, Morven, Sheehan, Sharon, Stockdale, Lisa, Thomas, Zita-Rose Manjaly, Lopez-Ramon, Raquel, Poulton, Ian, Lawrie, Alison, Vermaak, Samantha, Le Vert, Alexandre, Del Campo, Judith, Hill, Fergal, Moss, Paul, McShane, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786162/
https://ncbi.nlm.nih.gov/pubmed/26854906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2016.01.062
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