The structure of a Burkholderia pseudomallei immunophilin–inhibitor complex reveals new approaches to antimicrobial development

Por Norville, Isobel H., O'Shea, Katherine, Sarkar-Tyson, Mitali, Zheng, Suxin, Titball, Richard W., Varani, Gabriele, Harmer, Nicholas J.
Publicado em 2011

Disarming Burkholderia pseudomallei: Structural and Functional Characterization of a Disulfide Oxidoreductase (DsbA) Required for Virulence In Vivo

Por Ireland, Philip M., McMahon, Róisín M., Marshall, Laura E., Halili, Maria, Furlong, Emily, Tay, Stephanie, Martin, Jennifer L., Sarkar-Tyson, Mitali
Publicado em 2014

A Burkholderia pseudomallei Macrophage Infectivity Potentiator-Like Protein Has Rapamycin-Inhibitable Peptidylprolyl Isomerase Activity and Pleiotropic Effects on Virulence

Por Norville, Isobel H., Harmer, Nicholas J., Harding, Sarah V., Fischer, Gunter, Keith, Karen E., Brown, Katherine A., Sarkar-Tyson, Mitali, Titball, Richard W.
Publicado em 2011

Identification of a LolC Homologue in Burkholderia pseudomallei, a Novel Protective Antigen for Melioidosis

Por Harland, David N., Chu, Karen, Haque, Ashraful, Nelson, Michelle, Walker, Nicola J., Sarkar-Tyson, Mitali, Atkins, Timothy P., Moore, Benjamin, Brown, Katherine A., Bancroft, Gregory, Titball, Richard W., Atkins, Helen S.
Publicado em 2007

Characterization of the Burkholderia pseudomallei K96243 Capsular Polysaccharide I Coding Region

Por Cuccui, Jon, Milne, Timothy S., Harmer, Nicholas, George, Alison J., Harding, Sarah V., Dean, Rachel E., Scott, Andrew E., Sarkar-Tyson, Mitali, Wren, Brendan W., Titball, Richard W., Prior, Joann L.
Publicado em 2012

Genome-Wide Saturation Mutagenesis of Burkholderia pseudomallei K96243 Predicts Essential Genes and Novel Targets for Antimicrobial Development

Por Moule, Madeleine G., Hemsley, Claudia M., Seet, Qihui, Guerra-Assunção, José Afonso, Lim, Jiali, Sarkar-Tyson, Mitali, Clark, Taane G., Tan, Patrick B. O., Titball, Richard W., Cuccui, Jon, Wren, Brendan W.
Publicado em 2014

A Noise Trimming and Positional Significance of Transposon Insertion System to Identify Essential Genes in Yersinia pestis

Por Yang, Zheng Rong, Bullifent, Helen L., Moore, Karen, Paszkiewicz, Konrad, Saint, Richard J., Southern, Stephanie J., Champion, Olivia L., Senior, Nicola J., Sarkar-Tyson, Mitali, Oyston, Petra C. F., Atkins, Timothy P., Titball, Richard W.
Publicado no Sci Rep (2017)

Global Map of Growth-Regulated Gene Expression in Burkholderia pseudomallei, the Causative Agent of Melioidosis

Por Rodrigues, Fiona, Sarkar-Tyson, Mitali, Harding, Sarah V., Sim, Siew Hoon, Chua, Hui Hoon, Lin, Chi Ho, Han, Xu, Karuturi, R. Krishna M., Sung, Ken, Yu, Kun, Chen, Wei, Atkins, Timothy P., Titball, Richard W., Tan, Patrick
Publicado em 2006

A Genomic Survey of Positive Selection in Burkholderia pseudomallei Provides Insights into the Evolution of Accidental Virulence

Por Nandi, Tannistha, Ong, Catherine, Singh, Arvind Pratap, Boddey, Justin, Atkins, Timothy, Sarkar-Tyson, Mitali, Essex-Lopresti, Angela E., Chua, Hui Hoon, Pearson, Talima, Kreisberg, Jason F., Nilsson, Christina, Ariyaratne, Pramila, Ronning, Catherine, Losada, Liliana, Ruan, Yijun, Sung, Wing-Kin, Woods, Donald, Titball, Richard W., Beacham, Ifor, Peak, Ian, Keim, Paul, Nierman, William C., Tan, Patrick
Publicado em 2010

A Structural Biology Approach Enables the Development of Antimicrobials Targeting Bacterial Immunophilins

Por Begley, Darren W., Fox, David, Jenner, Dominic, Juli, Christina, Pierce, Phillip G., Abendroth, Jan, Muruthi, Muigai, Safford, Kris, Anderson, Vanessa, Atkins, Kateri, Barnes, Steve R., Moen, Spencer O., Raymond, Amy C., Stacy, Robin, Myler, Peter J., Staker, Bart L., Harmer, Nicholas J., Norville, Isobel H., Holzgrabe, Ulrike, Sarkar-Tyson, Mitali, Edwards, Thomas E., Lorimer, Donald D.
Publicado em 2014

Burkholderia pseudomallei sequencing identifies genomic clades with distinct recombination, accessory, and epigenetic profiles

Por Nandi, Tannistha, Holden, Matthew T.G., Didelot, Xavier, Mehershahi, Kurosh, Boddey, Justin A., Beacham, Ifor, Peak, Ian, Harting, John, Baybayan, Primo, Guo, Yan, Wang, Susana, How, Lee Chee, Sim, Bernice, Essex-Lopresti, Angela, Sarkar-Tyson, Mitali, Nelson, Michelle, Smither, Sophie, Ong, Catherine, Aw, Lay Tin, Hoon, Chua Hui, Michell, Stephen, Studholme, David J., Titball, Richard, Chen, Swaine L., Parkhill, Julian, Tan, Patrick
Publicado no Genome Res (2015)

Burkholderia pseudomallei sequencing identifies genomic clades with distinct recombination, accessory, and epigenetic profiles

Por Nandi, Tannistha, Holden, Matthew T.G., Didelot, Xavier, Mehershahi, Kurosh, Boddey, Justin A., Beacham, Ifor, Peak, Ian, Harting, John, Baybayan, Primo, Guo, Yan, Wang, Susana, How, Lee Chee, Sim, Bernice, Essex-Lopresti, Angela, Sarkar-Tyson, Mitali, Nelson, Michelle, Smither, Sophie, Ong, Catherine, Aw, Lay Tin, Hoon, Chua Hui, Michell, Stephen, Studholme, David J., Titball, Richard, Chen, Swaine L., Parkhill, Julian, Tan, Patrick
Publicado no Genome Res (2015)

A Burkholderia pseudomallei Toxin Inhibits Helicase Activity of Translation Factor eIF4A

Por Cruz, Abimael, Hautbergue, Guillaume M., Artymiuk, Peter J., Baker, Patrick J., Bokori-Brown, Monika, Chang, Chung-Te, Dickman, Mark J., Essex-Lopresti, Angela, Harding, Sarah V., Mahadi, Nor Muhammad, Marshall, Laura E., Mobbs, George W., Mohamed, Rahmah, Nathan, Sheila, Ngugi, Sarah A., Ong, Catherine, Ooi, Wen Fong, Partridge, Lynda J., Phillips, Helen L., Raih, M. Firdaus, Ruzhenikov, Sergei, Sarkar-Tyson, Mitali, Sedelnikova, Svetlana E., Smither, Sophie J., Tan, Patrick, Titball, Richard W., Wilson, Stuart A., Rice, David W.
Publicado em 2011