Disarming Burkholderia pseudomallei: Structural and Functional Characterization of a Disulfide Oxidoreductase (DsbA) Required for Virulence In Vivo

Aims: The intracellular pathogen Burkholderia pseudomallei causes the disease melioidosis, a major source of morbidity and mortality in southeast Asia and northern Australia. The need to develop novel antimicrobials is compounded by the absence of a licensed vaccine and the bacterium's resistan...

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Bibliographic Details
Main Authors: Ireland, Philip M., McMahon, Róisín M., Marshall, Laura E., Halili, Maria, Furlong, Emily, Tay, Stephanie, Martin, Jennifer L., Sarkar-Tyson, Mitali
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2014
Subjects:
Original Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901323/
https://ncbi.nlm.nih.gov/pubmed/23901809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5375
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