Genome-Wide Saturation Mutagenesis of Burkholderia pseudomallei K96243 Predicts Essential Genes and Novel Targets for Antimicrobial Development

Burkholderia pseudomallei is the causative agent of melioidosis, an often fatal infectious disease for which there is no vaccine. B. pseudomallei is listed as a tier 1 select agent, and as current therapeutic options are limited due to its natural resistance to most antibiotics, the development of n...

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Detalhes bibliográficos
Main Authors: Moule, Madeleine G., Hemsley, Claudia M., Seet, Qihui, Guerra-Assunção, José Afonso, Lim, Jiali, Sarkar-Tyson, Mitali, Clark, Taane G., Tan, Patrick B. O., Titball, Richard W., Cuccui, Jon, Wren, Brendan W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950516/
https://ncbi.nlm.nih.gov/pubmed/24520057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00926-13
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