Genome-Wide Saturation Mutagenesis of Burkholderia pseudomallei K96243 Predicts Essential Genes and Novel Targets for Antimicrobial Development

Burkholderia pseudomallei is the causative agent of melioidosis, an often fatal infectious disease for which there is no vaccine. B. pseudomallei is listed as a tier 1 select agent, and as current therapeutic options are limited due to its natural resistance to most antibiotics, the development of n...

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Bibliografske podrobnosti
Main Authors: Moule, Madeleine G., Hemsley, Claudia M., Seet, Qihui, Guerra-Assunção, José Afonso, Lim, Jiali, Sarkar-Tyson, Mitali, Clark, Taane G., Tan, Patrick B. O., Titball, Richard W., Cuccui, Jon, Wren, Brendan W.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Microbiology 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950516/
https://ncbi.nlm.nih.gov/pubmed/24520057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00926-13
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