The TGFβ-induced phosphorylation and activation of p38 mitogen-activated protein kinase is mediated by MAP3K4 and MAP3K10 but not TAK1

di Sapkota, Gopal P.
Pubblicazione 2013

The emerging roles of deubiquitylating enzymes (DUBs) in the TGFβ and BMP pathways

di Herhaus, Lina, Sapkota, Gopal P.
Pubblicato in Cell Signal (2014)

The FAM83 family of proteins: from pseudo-PLDs to anchors for CK1 isoforms

di Bozatzi, Polyxeni, Sapkota, Gopal P.
Pubblicato in Biochem Soc Trans (2018)

Mitotic kinase anchoring proteins: the navigators of cell division

di Fulcher, Luke J, Sapkota, Gopal P
Pubblicato in Cell Cycle (2020)

Functions and regulation of the serine/threonine protein kinase CK1 family: moving beyond promiscuity

di Fulcher, Luke J., Sapkota, Gopal P.
Pubblicato in Biochem J (2020)

Advances in targeted degradation of endogenous proteins

di Röth, Sascha, Fulcher, Luke J., Sapkota, Gopal P.
Pubblicato in Cell Mol Life Sci (2019)

IMiDs induce FAM83F degradation via an interaction with CK1α to attenuate Wnt signalling

di Dunbar, Karen, Macartney, Thomas J, Sapkota, Gopal P
Pubblicato in Life Sci Alliance (2020)

Regulation of the transforming growth factor β pathway by reversible ubiquitylation

di Al-Salihi, Mazin A., Herhaus, Lina, Sapkota, Gopal P.
Pubblicazione 2012

USP11 augments TGFβ signalling by deubiquitylating ALK5

di Al-Salihi, Mazin A., Herhaus, Lina, Macartney, Thomas, Sapkota, Gopal P.
Pubblicazione 2012

OTUB1 enhances TGFβ signalling by inhibiting the ubiquitylation and degradation of active SMAD2/3

di Herhaus, Lina, Al-Salihi, Mazin, Macartney, Thomas, Weidlich, Simone, Sapkota, Gopal P.
Pubblicazione 2013

Identification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndrom...

di Sapkota, Gopal P, Boudeau, Jérôme, Deak, Maria, Kieloch, Agnieszka, Morrice, Nick, Alessi, Dario R
Pubblicazione 2002

Rapid generation of endogenously driven transcriptional reporters in cells through CRISPR/Cas9

di Rojas-Fernandez, Alejandro, Herhaus, Lina, Macartney, Thomas, Lachaud, Christophe, Hay, Ronald T., Sapkota, Gopal P.
Pubblicato in Sci Rep (2015)

Targeting endogenous proteins for degradation through the affinity-directed protein missile system

di Fulcher, Luke J., Hutchinson, Luke D., Macartney, Thomas J., Turnbull, Craig, Sapkota, Gopal P.
Pubblicato in Open Biol (2017)

An affinity-directed protein missile system for targeted proteolysis

di Fulcher, Luke J., Macartney, Thomas, Bozatzi, Polyxeni, Hornberger, Annika, Rojas-Fernandez, Alejandro, Sapkota, Gopal P.
Pubblicato in Open Biol (2016)

FAM83F regulates canonical Wnt signalling through an interaction with CK1α

di Dunbar, Karen, Jones, Rebecca A, Dingwell, Kevin, Macartney, Thomas J, Smith, James C, Sapkota, Gopal P
Pubblicato in Life Sci Alliance (2020)

Protein associated with SMAD1 (PAWS1/FAM83G) is a substrate for type I bone morphogenetic protein receptors and modulates bone morphogenetic protein signalling

di Vogt, Janis, Dingwell, Kevin S., Herhaus, Lina, Gourlay, Robert, Macartney, Thomas, Campbell, David, Smith, James C., Sapkota, Gopal P.
Pubblicazione 2014

Targeting Endogenous K-RAS for Degradation through the Affinity-Directed Protein Missile System

di Röth, Sascha, Macartney, Thomas J., Konopacka, Agnieszka, Chan, Kwok-Ho, Zhou, Houjiang, Queisser, Markus A., Sapkota, Gopal P.
Pubblicato in Cell Chem Biol (2020)

Salt-inducible kinases (SIKs) regulate TGFβ-mediated transcriptional and apoptotic responses

di Hutchinson, Luke D., Darling, Nicola J., Nicolaou, Stephanos, Gori, Ilaria, Squair, Daniel R., Cohen, Philip, Hill, Caroline S., Sapkota, Gopal P.
Pubblicato in Cell Death Dis (2020)

Casein kinase 2 (CK2) phosphorylates the deubiquitylase OTUB1 at Ser(16) to trigger its nuclear localization

di Herhaus, Lina, Perez-Oliva, Ana B., Cozza, Giorgio, Gourlay, Robert, Weidlich, Simone, Campbell, David G., Pinna, Lorenzo A., Sapkota, Gopal P.
Pubblicato in Sci Signal (2015)

Brd4‐Brd2 isoform switching coordinates pluripotent exit and Smad2‐dependent lineage specification

di Fernandez‐Alonso, Rosalia, Davidson, Lindsay, Hukelmann, Jens, Zengerle, Michael, Prescott, Alan R, Lamond, Angus, Ciulli, Alessio, Sapkota, Gopal P, Findlay, Greg M
Pubblicato in EMBO Rep (2017)