FAM83F regulates canonical Wnt signalling through an interaction with CK1α

The function of the FAM83F protein, like the functions of many members of the FAM83 family, is poorly understood. Here, we show that injection of Fam83f mRNA into Xenopus embryos causes axis duplication, a phenotype indicative of enhanced Wnt signalling. Consistent with this, overexpression of FAM83...

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Detalhes bibliográficos
Publicado no:Life Sci Alliance
Main Authors: Dunbar, Karen, Jones, Rebecca A, Dingwell, Kevin, Macartney, Thomas J, Smith, James C, Sapkota, Gopal P
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768192/
https://ncbi.nlm.nih.gov/pubmed/33361109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000805
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