Genetic Predisposition Favors the Acquisition of Stable Artemisinin Resistance in Malaria Parasites

Por Beez, Dorothee, Sanchez, Cecilia P., Stein, Wilfred D., Lanzer, Michael
Publicado em 2011

Knockout of the peroxiredoxin 5 homologue PFAOP does not affect the artemisinin susceptibility of Plasmodium falciparum

Por Djuika, Carine F., Staudacher, Verena, Sanchez, Cecilia P., Lanzer, Michael, Deponte, Marcel
Publicado no Sci Rep (2017)

Differential Stimulation of the Na(+)/H(+) Exchanger Determines Chloroquine Uptake in Plasmodium falciparum

Por Wünsch, Stefan, Sanchez, Cecilia P., Gekle, Michael, Große-Wortmann, Lars, Wiesner, Jochen, Lanzer, Michael
Publicado em 1998

Experimental Evolution of Resistance to Artemisinin Combination Therapy Results in Amplification of the mdr1 Gene in a Rodent Malaria Parasite

Por Rodrigues, Louise A., Henriques, Gisela, Borges, Sofia T., Hunt, Paul, Sanchez, Cecília P., Martinelli, Axel, Cravo, Pedro
Publicado em 2010

Identification of genetic markers of resistance to Artemisinin Combination Therapy in the rodent model Plasmodium chabaudi

Por Rodrigues, Louise A, Henriques, Gisela, Borges, Sofia T, Hunt, Paul, Sanchez, Cecília P, Martinelli, Axel, Cravo, Pedro
Publicado em 2010

Differences in trans-stimulated chloroquine efflux kinetics are linked to PfCRT in Plasmodium falciparum

Por Sanchez, Cecilia P., Rohrbach, Petra, McLean, Jeremy E., Fidock, David A., Stein, Wilfred D., Lanzer, Michael
Publicado em 2007

Cytoadhesion of Plasmodium falciparum–infected erythrocytes to chondroitin-4-sulfate is cooperative and shear enhanced

Por Rieger, Harden, Yoshikawa, Hiroshi Y., Quadt, Katharina, Nielsen, Morten A., Sanchez, Cecilia P., Salanti, Ali, Tanaka, Motomu, Lanzer, Michael
Publicado no Blood (2015)

Hemoglobin S and C affect protein export in Plasmodium falciparum-infected erythrocytes

Por Kilian, Nicole, Srismith, Sirikamol, Dittmer, Martin, Ouermi, Djeneba, Bisseye, Cyrille, Simpore, Jacques, Cyrklaff, Marek, Sanchez, Cecilia P., Lanzer, Michael
Publicado no Biol Open (2015)

Differential time‐dependent volumetric and surface area changes and delayed induction of new permeation pathways in P. falciparum‐infected hemoglobinopathic erythrocytes

Por Waldecker, Mailin, Dasanna, Anil K., Lansche, Christine, Linke, Marco, Srismith, Sirikamol, Cyrklaff, Marek, Sanchez, Cecilia P., Schwarz, Ulrich S., Lanzer, Michael
Publicado no Cell Microbiol (2016)

A HECT Ubiquitin-Protein Ligase as a Novel Candidate Gene for Altered Quinine and Quinidine Responses in Plasmodium falciparum

Por Sanchez, Cecilia P., Liu, Chia-Hao, Mayer, Sybille, Nurhasanah, Astutiati, Cyrklaff, Marek, Mu, Jianbing, Ferdig, Michael T., Stein, Wilfred D., Lanzer, Michael
Publicado em 2014

Iron is a substrate of the Plasmodium falciparum chloroquine resistance transporter PfCRT in Xenopus oocytes

Por Bakouh, Naziha, Bellanca, Sebastiano, Nyboer, Britta, Moliner Cubel, Sonia, Karim, Zoubida, Sanchez, Cecilia P., Stein, Wilfred D., Planelles, Gabrielle, Lanzer, Michael
Publicado no J Biol Chem (2017)

Genetic linkage of pfmdr1 with food vacuolar solute import in Plasmodium falciparum

Por Rohrbach, Petra, Sanchez, Cecilia P, Hayton, Karen, Friedrich, Oliver, Patel, Jigar, Sidhu, Amar Bir Singh, Ferdig, Michael T, Fidock, David A, Lanzer, Michael
Publicado em 2006

Prokaryotic ancestry and gene fusion of a dual localized peroxiredoxin in malaria parasites

Por Djuika, Carine F., Huerta-Cepas, Jaime, Przyborski, Jude M., Deil, Sophia, Sanchez, Cecilia P., Doerks, Tobias, Bork, Peer, Lanzer, Michael, Deponte, Marcel
Publicado no Microb Cell (2015)

Multiple Drugs Compete for Transport via the Plasmodium falciparum Chloroquine Resistance Transporter at Distinct but Interdependent Sites

Por Bellanca, Sebastiano, Summers, Robert L., Meyrath, Max, Dave, Anurag, Nash, Megan N., Dittmer, Martin, Sanchez, Cecilia P., Stein, Wilfred D., Martin, Rowena E., Lanzer, Michael
Publicado no J Biol Chem (2014)

Oxidative insult can induce malaria-protective trait of sickle and fetal erythrocytes

Por Cyrklaff, Marek, Srismith, Sirikamol, Nyboer, Britta, Burda, Kvetoslava, Hoffmann, Angelika, Lasitschka, Felix, Adjalley, Sophie, Bisseye, Cyrille, Simpore, Jacques, Mueller, Ann-Kristin, Sanchez, Cecilia P., Frischknecht, Friedrich, Lanzer, Michael
Publicado no Nat Commun (2016)

Export of virulence proteins by malaria-infected erythrocytes involves remodeling of host actin cytoskeleton

Por Rug, Melanie, Cyrklaff, Marek, Mikkonen, Antti, Lemgruber, Leandro, Kuelzer, Simone, Sanchez, Cecilia P., Thompson, Jennifer, Hanssen, Eric, O’Neill, Matthew, Langer, Christine, Lanzer, Michael, Frischknecht, Friedrich, Maier, Alexander G., Cowman, Alan F.
Publicado no Blood (2014)

SC83288 is a clinical development candidate for the treatment of severe malaria

Por Pegoraro, Stefano, Duffey, Maëlle, Otto, Thomas D, Wang, Yulin, Rösemann, Roman, Baumgartner, Roland, Fehler, Stefanie K, Lucantoni, Leonardo, Avery, Vicky M, Moreno-Sabater, Alicia, Mazier, Dominique, Vial, Henri J, Strobl, Stefan, Sanchez, Cecilia P, Lanzer, Michael
Publicado no Nat Commun (2017)

Erratum: SC83288 is a clinical development candidate for the treatment of severe malaria

Por Pegoraro, Stefano, Duffey, Maëlle, Otto, Thomas D., Wang, Yulin, Rösemann, Roman, Baumgartner, Roland, Fehler, Stefanie K., Lucantoni, Leonardo, Avery, Vicky M., Moreno-Sabater, Alicia, Mazier, Dominique, Vial, Henri J., Strobl, Stefan, Sanchez, Cecilia P., Lanzer, Michael
Publicado no Nat Commun (2017)

A global view of the nonprotein-coding transcriptome in Plasmodium falciparum

Por Raabe, Carsten A., Sanchez, Cecilia P., Randau, Gerrit, Robeck, Thomas, Skryabin, Boris V., Chinni, Suresh V., Kube, Michael, Reinhardt, Richard, Ng, Guey Hooi, Manickam, Ravichandran, Kuryshev, Vladimir Y., Lanzer, Michael, Brosius, Juergen, Tang, Thean Hock, Rozhdestvensky, Timofey S.
Publicado em 2010

Diverse mutational pathways converge on saturable chloroquine transport via the malaria parasite’s chloroquine resistance transporter

Por Summers, Robert L., Dave, Anurag, Dolstra, Tegan J., Bellanca, Sebastiano, Marchetti, Rosa V., Nash, Megan N., Richards, Sashika N., Goh, Valerie, Schenk, Robyn L., Stein, Wilfred D., Kirk, Kiaran, Sanchez, Cecilia P., Lanzer, Michael, Martin, Rowena E.
Publicado em 2014