A HECT Ubiquitin-Protein Ligase as a Novel Candidate Gene for Altered Quinine and Quinidine Responses in Plasmodium falciparum

The emerging resistance to quinine jeopardizes the efficacy of a drug that has been used in the treatment of malaria for several centuries. To identify factors contributing to differential quinine responses in the human malaria parasite Plasmodium falciparum, we have conducted comparative quantitati...

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Detalhes bibliográficos
Main Authors: Sanchez, Cecilia P., Liu, Chia-Hao, Mayer, Sybille, Nurhasanah, Astutiati, Cyrklaff, Marek, Mu, Jianbing, Ferdig, Michael T., Stein, Wilfred D., Lanzer, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022464/
https://ncbi.nlm.nih.gov/pubmed/24830312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004382
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