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A HECT Ubiquitin-Protein Ligase as a Novel Candidate Gene for Altered Quinine and Quinidine Responses in Plasmodium falciparum

The emerging resistance to quinine jeopardizes the efficacy of a drug that has been used in the treatment of malaria for several centuries. To identify factors contributing to differential quinine responses in the human malaria parasite Plasmodium falciparum, we have conducted comparative quantitati...

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Bibliografski detalji
Glavni autori: Sanchez, Cecilia P., Liu, Chia-Hao, Mayer, Sybille, Nurhasanah, Astutiati, Cyrklaff, Marek, Mu, Jianbing, Ferdig, Michael T., Stein, Wilfred D., Lanzer, Michael
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022464/
https://ncbi.nlm.nih.gov/pubmed/24830312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004382
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