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Oxidative insult can induce malaria-protective trait of sickle and fetal erythrocytes

Plasmodium falciparum infections can cause severe malaria, but not every infected person develops life-threatening complications. In particular, carriers of the structural haemoglobinopathies S and C and infants are protected from severe disease. Protection is associated with impaired parasite-induc...

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Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Cyrklaff, Marek, Srismith, Sirikamol, Nyboer, Britta, Burda, Kvetoslava, Hoffmann, Angelika, Lasitschka, Felix, Adjalley, Sophie, Bisseye, Cyrille, Simpore, Jacques, Mueller, Ann-Kristin, Sanchez, Cecilia P., Frischknecht, Friedrich, Lanzer, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105170/
https://ncbi.nlm.nih.gov/pubmed/27824335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13401
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