Dissecting innate immunity by germline mutagenesis

Por Rutschmann, Sophie, Hoebe, Kasper
Publicado em 2008

Dissecting immunity by germline mutagenesis

Por Choi, Onjee, Rutschmann, Sophie
Publicado em 2012

N-Ethyl-N-nitrosourea mutagenesis in the mouse provides strong genetic and in vivo evidence for the role of the Caspase Recruitment Domain (CARD) of CARD-MAGUK1 in T regulatory cel...

Por Salisbury, Emma M, Wang, Lihui, Choi, Onjee, Rutschmann, Sophie, Ashton-Rickardt, Philip G
Publicado em 2014

Rab27a is a key component of the secretory machinery of azurophilic granules in granulocytes

Por Munafó, Daniela B., Johnson, Jennifer L., Ellis, Beverly A., Rutschmann, Sophie, Beutler, Bruce, Catz, Sergio D.
Publicado em 2007

Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response

Por Brandl, Katharina, Rutschmann, Sophie, Li, Xiaohong, Du, Xin, Xiao, Nengming, Schnabl, Bernd, Brenner, David A., Beutler, Bruce
Publicado em 2009

Disruption of copper homeostasis due to a mutation of Atp7a delays the onset of prion disease

Por Siggs, Owen M., Cruite, Justin T., Du, Xin, Rutschmann, Sophie, Masliah, Eliezer, Beutler, Bruce, Oldstone, Michael B. A.
Publicado em 2012

Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis

Por Crozat, Karine, Hoebe, Kasper, Ugolini, Sophie, Hong, Nancy A., Janssen, Edith, Rutschmann, Sophie, Mudd, Suzanne, Sovath, Sosathya, Vivier, Eric, Beutler, Bruce
Publicado em 2007

Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis

Por Crozat, Karine, Hoebe, Kasper, Ugolini, Sophie, Hong, Nancy A., Janssen, Edith, Rutschmann, Sophie, Mudd, Suzanne, Sovath, Sosathya, Vivier, Eric, Beutler, Bruce
Publicado em 2008

Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells

Por Blasius, Amanda L., Arnold, Carrie N., Georgel, Philippe, Rutschmann, Sophie, Xia, Yu, Lin, Pei, Ross, Charles, Li, Xiaohong, Smart, Nora G., Beutler, Bruce
Publicado em 2010

A deficiency in nucleoside salvage impairs murine lymphocyte development, homeostasis and survival()

Por Choi, Onjee, Heathcote, Dean A., Ho, Ka-Kei, Müller, Phillip J., Ghani, Hazim, Lam, Eric W.-F., Ashton-Rickardt, Philip G., Rutschmann, Sophie
Publicado em 2012

Hypomorphic mutation in the site-1 protease Mbtps1 endows resistance to persistent viral infection in a cell specific manner

Por Popkin, Daniel L., Teijaro, John R., Sullivan, Brian M., Urata, Shuzo, Rutschmann, Sophie, de la Torre, Juan Carlos, Kunz, Stefan, Beutler, Bruce, Oldstone, Michael
Publicado em 2011

Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis

Por Jiang, Zhengfan, Georgel, Philippe, Li, Chenglong, Choe, Jungwoo, Crozat, Karine, Rutschmann, Sophie, Du, Xin, Bigby, Tim, Mudd, Suzanne, Sovath, Sosathya, Wilson, Ian A., Olson, Arthur, Beutler, Bruce
Publicado em 2006

A Toll-Like Receptor 2-Responsive Lipid Effector Pathway Protects Mammals against Skin Infections with Gram-Positive Bacteria

Por Georgel, Philippe, Crozat, Karine, Lauth, Xavier, Makrantonaki, Evgenia, Seltmann, Holger, Sovath, Sosathya, Hoebe, Kasper, Du, Xin, Rutschmann, Sophie, Jiang, Zhengfan, Bigby, Timothy, Nizet, Victor, Zouboulis, Christos C., Beutler, Bruce
Publicado em 2005

Hypopigmentation and Maternal-Zygotic Embryonic Lethality Caused by a Hypomorphic Mbtps1 Mutation in Mice

Por Rutschmann, Sophie, Crozat, Karine, Li, Xiaohong, Du, Xin, Hanselman, Jeffrey C., Shigeoka, Alana A., Brandl, Katharina, Popkin, Daniel L., McKay, Dianne B., Xia, Yu, Moresco, Eva Marie Y., Beutler, Bruce
Publicado em 2012

ENU-induced phenovariance in mice: inferences from 587 mutations

Por Arnold, Carrie N, Barnes, Michael J, Berger, Michael, Blasius, Amanda L, Brandl, Katharina, Croker, Ben, Crozat, Karine, Du, Xin, Eidenschenk, Celine, Georgel, Philippe, Hoebe, Kasper, Huang, Hua, Jiang, Zhengfan, Krebs, Philippe, La Vine, Diantha, Li, Xiaohong, Lyon, Stephen, Moresco, Eva Marie Y, Murray, Anne R, Popkin, Daniel L, Rutschmann, Sophie, Siggs, Owen M, Smart, Nora G, Sun, Lei, Tabeta, Koichi, Webster, Victoria, Tomisato, Wataru, Won, Sungyong, Xia, Yu, Xiao, Nengming, Beutler, Bruce
Publicado em 2012