Dissecting innate immunity by germline mutagenesis

מאת Rutschmann, Sophie, Hoebe, Kasper
יצא לאור 2008

Dissecting immunity by germline mutagenesis

מאת Choi, Onjee, Rutschmann, Sophie
יצא לאור 2012

N-Ethyl-N-nitrosourea mutagenesis in the mouse provides strong genetic and in vivo evidence for the role of the Caspase Recruitment Domain (CARD) of CARD-MAGUK1 in T regulatory cel...

מאת Salisbury, Emma M, Wang, Lihui, Choi, Onjee, Rutschmann, Sophie, Ashton-Rickardt, Philip G
יצא לאור 2014

Rab27a is a key component of the secretory machinery of azurophilic granules in granulocytes

מאת Munafó, Daniela B., Johnson, Jennifer L., Ellis, Beverly A., Rutschmann, Sophie, Beutler, Bruce, Catz, Sergio D.
יצא לאור 2007

Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response

מאת Brandl, Katharina, Rutschmann, Sophie, Li, Xiaohong, Du, Xin, Xiao, Nengming, Schnabl, Bernd, Brenner, David A., Beutler, Bruce
יצא לאור 2009

Disruption of copper homeostasis due to a mutation of Atp7a delays the onset of prion disease

מאת Siggs, Owen M., Cruite, Justin T., Du, Xin, Rutschmann, Sophie, Masliah, Eliezer, Beutler, Bruce, Oldstone, Michael B. A.
יצא לאור 2012

Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis

מאת Crozat, Karine, Hoebe, Kasper, Ugolini, Sophie, Hong, Nancy A., Janssen, Edith, Rutschmann, Sophie, Mudd, Suzanne, Sovath, Sosathya, Vivier, Eric, Beutler, Bruce
יצא לאור 2007

Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis

מאת Crozat, Karine, Hoebe, Kasper, Ugolini, Sophie, Hong, Nancy A., Janssen, Edith, Rutschmann, Sophie, Mudd, Suzanne, Sovath, Sosathya, Vivier, Eric, Beutler, Bruce
יצא לאור 2008

Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells

מאת Blasius, Amanda L., Arnold, Carrie N., Georgel, Philippe, Rutschmann, Sophie, Xia, Yu, Lin, Pei, Ross, Charles, Li, Xiaohong, Smart, Nora G., Beutler, Bruce
יצא לאור 2010

A deficiency in nucleoside salvage impairs murine lymphocyte development, homeostasis and survival()

מאת Choi, Onjee, Heathcote, Dean A., Ho, Ka-Kei, Müller, Phillip J., Ghani, Hazim, Lam, Eric W.-F., Ashton-Rickardt, Philip G., Rutschmann, Sophie
יצא לאור 2012

Hypomorphic mutation in the site-1 protease Mbtps1 endows resistance to persistent viral infection in a cell specific manner

מאת Popkin, Daniel L., Teijaro, John R., Sullivan, Brian M., Urata, Shuzo, Rutschmann, Sophie, de la Torre, Juan Carlos, Kunz, Stefan, Beutler, Bruce, Oldstone, Michael
יצא לאור 2011

Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis

מאת Jiang, Zhengfan, Georgel, Philippe, Li, Chenglong, Choe, Jungwoo, Crozat, Karine, Rutschmann, Sophie, Du, Xin, Bigby, Tim, Mudd, Suzanne, Sovath, Sosathya, Wilson, Ian A., Olson, Arthur, Beutler, Bruce
יצא לאור 2006

A Toll-Like Receptor 2-Responsive Lipid Effector Pathway Protects Mammals against Skin Infections with Gram-Positive Bacteria

מאת Georgel, Philippe, Crozat, Karine, Lauth, Xavier, Makrantonaki, Evgenia, Seltmann, Holger, Sovath, Sosathya, Hoebe, Kasper, Du, Xin, Rutschmann, Sophie, Jiang, Zhengfan, Bigby, Timothy, Nizet, Victor, Zouboulis, Christos C., Beutler, Bruce
יצא לאור 2005

C1q restrains autoimmunity and viral infection by regulating CD8(+) T-cell metabolism

מאת Ling, Guang Sheng, Crawford, Greg, Buang, Norzawani, Bartok, Istvan, Tian, Kunyuan, Thielens, Nicole M, Bally, Isabelle, Harker, James A, Ashton-Rickardt, Philip G, Rutschmann, Sophie, Strid, Jessica, Botto, Marina
הוצא לאור ב Science (2018)

Hypopigmentation and Maternal-Zygotic Embryonic Lethality Caused by a Hypomorphic Mbtps1 Mutation in Mice

מאת Rutschmann, Sophie, Crozat, Karine, Li, Xiaohong, Du, Xin, Hanselman, Jeffrey C., Shigeoka, Alana A., Brandl, Katharina, Popkin, Daniel L., McKay, Dianne B., Xia, Yu, Moresco, Eva Marie Y., Beutler, Bruce
יצא לאור 2012

ENU-induced phenovariance in mice: inferences from 587 mutations

מאת Arnold, Carrie N, Barnes, Michael J, Berger, Michael, Blasius, Amanda L, Brandl, Katharina, Croker, Ben, Crozat, Karine, Du, Xin, Eidenschenk, Celine, Georgel, Philippe, Hoebe, Kasper, Huang, Hua, Jiang, Zhengfan, Krebs, Philippe, La Vine, Diantha, Li, Xiaohong, Lyon, Stephen, Moresco, Eva Marie Y, Murray, Anne R, Popkin, Daniel L, Rutschmann, Sophie, Siggs, Owen M, Smart, Nora G, Sun, Lei, Tabeta, Koichi, Webster, Victoria, Tomisato, Wataru, Won, Sungyong, Xia, Yu, Xiao, Nengming, Beutler, Bruce
יצא לאור 2012