Liver function and dysfunction: a unique window into the physiological reach of ER stress and the unfolded protein response

Por Rutkowski, D. Thomas
Publicado no FEBS J (2018)

Regulation of basal cellular physiology by the homeostatic unfolded protein response

Por Rutkowski, D. Thomas, Hegde, Ramanujan S.
Publicado em 2010

Endoplasmic reticulum stress impairs IL-4/IL-13 signaling through C/EBPβ-mediated transcriptional suppression

Por Arensdorf, Angela M., Thomas Rutkowski, D.
Publicado em 2013

Experimental reconstitution of chronic ER stress in the liver reveals feedback suppression of BiP mRNA expression

Por Gomez, Javier A, Rutkowski, D Thomas
Publicado no eLife (2016)

Substrate-specific regulation of the ribosome– translocon junction by N-terminal signal sequences

Por Rutkowski, D. Thomas, Lingappa, Vishwanath R., Hegde, Ramanujan S.
Publicado em 2001

Regulation of the transcriptome by ER stress: non-canonical mechanisms and physiological consequences

Por Arensdorf, Angela M., Diedrichs, Danilo, Rutkowski, D. Thomas
Publicado em 2013

Inhibition of fatty acid oxidation enhances oxidative protein folding and protects hepatocytes from endoplasmic reticulum stress

Por Tyra, Heather M., Spitz, Douglas R., Rutkowski, D. Thomas
Publicado em 2012

C/EBP Homologous Protein (CHOP) Contributes to Suppression of Metabolic Genes during Endoplasmic Reticulum Stress in the Liver

Por Chikka, Madhusudana R., McCabe, Diane DeZwaan, Tyra, Heather M., Rutkowski, D. Thomas
Publicado em 2013

Temporal clustering of gene expression links the metabolic transcription factor HNF4α to the ER stress-dependent gene regulatory network

Por Arensdorf, Angela M., DeZwaan McCabe, Diane, Kaufman, Randal J., Rutkowski, D. Thomas
Publicado em 2013

A data-entrained computational model for testing the regulatory logic of the vertebrate unfolded protein response

Por Diedrichs, Danilo R., Gomez, Javier A., Huang, Chun-Sing, Rutkowski, D. Thomas, Curtu, Rodica
Publicado no Mol Biol Cell (2018)

2-Deoxyglucose-induced toxicity is regulated by Bcl-2 family members and is enhanced by antagonizing Bcl-2 in lymphoma cell lines

Por Zagorodna, Oksana, Martin, Sean M., Rutkowski, D. Thomas, Kuwana, Tomomi, Spitz, Douglas R., Knudson, C. Michael
Publicado em 2011

Synthetic embryonic lethality upon deletion of the ER cochaperone p58(IPK) and the ER stress sensor ATF6α

Por Gomez, Javier A., Tyra, Heather M., McCabe, Diane DeZwaan, Olivier, Alicia K., Rutkowski, D. Thomas
Publicado em 2013

piggyBac-mediated phenotypic correction of factor VIII deficiency

Por Staber, Janice M, Pollpeter, Molly J, Arensdorf, Angela, Sinn, Patrick L, Rutkowski, D Thomas, McCray, Paul B
Publicado no Mol Ther Methods Clin Dev (2014)

The Stress-Regulated Transcription Factor CHOP Promotes Hepatic Inflammatory Gene Expression, Fibrosis, and Oncogenesis

Por DeZwaan-McCabe, Diane, Riordan, Jesse D., Arensdorf, Angela M., Icardi, Michael S., Dupuy, Adam J., Rutkowski, D. Thomas
Publicado em 2013

Influenza A Viral Replication Is Blocked by Inhibition of the Inositol-requiring Enzyme 1 (IRE1) Stress Pathway

Por Hassan, Ihab H., Zhang, Michael S., Powers, Linda S., Shao, Jian Q., Baltrusaitis, Jonas, Rutkowski, D. Thomas, Legge, Kevin, Monick, Martha M.
Publicado em 2012

An abnormality in glucocorticoid receptor expression differentiates steroid responders from nonresponders in keloid disease

Por Rutkowski, D., Syed, F., Matthews, L.C., Ray, D.W., McGrouther, D.A., Watson, R.E.B., Bayat, A.
Publicado no Br J Dermatol (2015)

Inositol-requiring Enzyme 1 Inhibits Respiratory Syncytial Virus Replication

Por Hassan, Ihab, Gaines, Kayla S., Hottel, Wesley J., Wishy, Ryan M., Miller, Sara E., Powers, Linda S., Rutkowski, D. Thomas, Monick, Martha M.
Publicado em 2014

The Role of p58(IPK) in Protecting the Stressed Endoplasmic Reticulum

Por Rutkowski, D. Thomas, Kang, Sang-Wook, Goodman, Alan G., Garrison, Jennifer L., Taunton, Jack, Katze, Michael G., Kaufman, Randal J., Hegde, Ramanujan S.
Publicado em 2007

Heightened Induction of Proapoptotic Signals in Response to Endoplasmic Reticulum Stress in Primary Fibroblasts from a Mouse Model of Longevity

Por Sadighi Akha, Amir A., Harper, James M., Salmon, Adam B., Schroeder, Bethany A., Tyra, Heather M., Rutkowski, D. Thomas, Miller, Richard A.
Publicado em 2011

Brain Endoplasmic Reticulum Stress Mechanistically Distinguishes the Saline-Intake and Hypertensive Response to DOCA-Salt

Por Jo, Fusakazu, Jo, Hiromi, Hilzendeger, Aline M., Thompson, Anthony P., Cassell, Martin D., Rutkowski, D. Thomas, Davisson, Robin L., Grobe, Justin L., Sigmund, Curt D.
Publicado no Hypertension (2015)