Influenza A Viral Replication Is Blocked by Inhibition of the Inositol-requiring Enzyme 1 (IRE1) Stress Pathway

Known therapies for influenza A virus infection are complicated by the frequent emergence of resistance. A therapeutic strategy that may escape viral resistance is targeting host cellular mechanisms involved in viral replication and pathogenesis. The endoplasmic reticulum (ER) stress response, also...

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Bibliografiske detaljer
Main Authors: Hassan, Ihab H., Zhang, Michael S., Powers, Linda S., Shao, Jian Q., Baltrusaitis, Jonas, Rutkowski, D. Thomas, Legge, Kevin, Monick, Martha M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281634/
https://ncbi.nlm.nih.gov/pubmed/22194594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.284695
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