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Opposite Roles of RNase and Kinase Activities of Inositol-Requiring Enzyme 1 (IRE1) on HSV-1 Replication

In response to the endoplasmic reticulum (ER) stress induced by herpes simplex virus type 1 (HSV-1) infection, host cells activate the unfolded protein response (UPR) to reduce the protein-folding burden in the ER. The regulation of UPR upon HSV-1 infection is complex, and the downstream effectors c...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Su, Airong, Wang, Huanru, Li, Yanlei, Wang, Xiaohui, Chen, Deyan, Wu, Zhiwei
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618002/
https://ncbi.nlm.nih.gov/pubmed/28832521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v9090235
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