Ubiquitination of Inositol-requiring Enzyme 1 (IRE1) by the E3 Ligase CHIP Mediates the IRE1/TRAF2/JNK Pathway

Deciphering the inositol-requiring enzyme 1 (IRE1) signaling pathway is fundamentally important for understanding the unfolded protein response (UPR). The ubiquitination of proteins residing on the endoplasmic reticulum (ER) membrane has been reported to be involved in the UPR, although the mechanis...

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Main Authors: Zhu, Xu, Zhang, Ju, Sun, Huiying, Jiang, Cuicui, Dong, Yusheng, Shan, Qiang, Su, Siyuan, Xie, Yingying, Xu, Ningzhi, Lou, Xiaomin, Liu, Siqi
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2014
Ábhair:
Cell Biology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215236/
https://ncbi.nlm.nih.gov/pubmed/25225294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.562868
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