Ubiquitination of Inositol-requiring Enzyme 1 (IRE1) by the E3 Ligase CHIP Mediates the IRE1/TRAF2/JNK Pathway

Deciphering the inositol-requiring enzyme 1 (IRE1) signaling pathway is fundamentally important for understanding the unfolded protein response (UPR). The ubiquitination of proteins residing on the endoplasmic reticulum (ER) membrane has been reported to be involved in the UPR, although the mechanis...

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Detalhes bibliográficos
Main Authors: Zhu, Xu, Zhang, Ju, Sun, Huiying, Jiang, Cuicui, Dong, Yusheng, Shan, Qiang, Su, Siyuan, Xie, Yingying, Xu, Ningzhi, Lou, Xiaomin, Liu, Siqi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215236/
https://ncbi.nlm.nih.gov/pubmed/25225294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.562868
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