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Endoplasmic reticulum stress impairs IL-4/IL-13 signaling through C/EBPβ-mediated transcriptional suppression

Activation of the unfolded protein response (UPR) by endoplasmic reticulum (ER) stress culminates in extensive gene regulation, with transcriptional upregulation of genes that improve the protein folding capacity of the organelle. However, a substantial number of genes are downregulated by ER stress...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Arensdorf, Angela M., Thomas Rutkowski, D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Company of Biologists 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757336/
https://ncbi.nlm.nih.gov/pubmed/23813955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.130757
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