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C/EBP Homologous Protein (CHOP) Contributes to Suppression of Metabolic Genes during Endoplasmic Reticulum Stress in the Liver

The unfolded protein response (UPR) senses stress in the endoplasmic reticulum (ER) and initiates signal transduction cascades that culminate in changes to gene regulation. Long recognized as a means for improving ER protein folding through up-regulation of ER chaperones, the UPR is increasingly rec...

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Detalhes bibliográficos
Main Authors: Chikka, Madhusudana R., McCabe, Diane DeZwaan, Tyra, Heather M., Rutkowski, D. Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567690/
https://ncbi.nlm.nih.gov/pubmed/23281479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.432344
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